腹膜播種陽性大腸癌の臨床病理学的検討

概要

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Indication of intensive therapy for colorectal cancer patients with dissemination was studied clinicopathologically. 30 of 605 patients (5.0%) that had received colorectal resection in our department had peritoneal dissemination; P1 13 cases, P2 9 cases, and P3 was 8 cases. Colorectal cancer patients with peritoneal dissemination had the following characteristics. 1. Patients with peritoneal dissemination were younger than those without peritoneal dissemination. 2. Right side colon cancer, invasive type, and poorly differentiated adenocarcinoma were recoginized more frequently in patients with peritoneal dissemination. 3. Advanced cases were recoginised more frequently in patients with peritoneal dissemination. Si was found in 9 cases (30.0%), synchronous liver metastasis was present in 9 cases (30.0%). 4. Prognosis of patients with neither liver metastasis nor N4 is better than those with liver metastasis or N4. 5. 2 cases survived more than 5 years after operation. They are P1 and P2, both without liver metastasis, R>n, and disseminated peritonium was resected. Our conclusion is that cases less than P2, without liver metastasis, R>n, are candidates for intensive therapy.
日本大腸肛門病学会の論文