Studies on Recurrence of Colorectal Cancer. Analysis of Clinical Factors Influencing on Disease Free Interval.:Analysis of Clinical Factors Influencing on Disease Free Interval

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In order to make effective follow up system for curative colorectal cancer, clinical factors influencing on "disease free interval" ; interval from resection of primary tumor to detection of recurrence were investigated statistically. The 551 cases of solitary colorectal cancer were operated on for cure between 1980 to 1986, and 87 cases of apparently recurrent cancer were obtained from our follow up cases. The first recurrent site of these cases were as follws ; 41 cases were liver metastasis, 16 cases were lung metastasis, 17 cases were local recurrence and 13 cases were others. The mean disease free interval of.liver metastasis was 19 months, lung metastasis was 20 months and local recurrence was 16 months. In the cases of liver and lung metastasis, disease free interval of Dukes'C cases was shorter than Dukes'A and B cases and that of cases whose preoperative CEA level were above normal limit was shorter than that of cases within normal limit, and all cases which had both incidences of Dukes'C and high CEA level were recurrent within two years after primary resection.So in these cases, it is important to make intensive follow up for haemorragic metastasis during earlier time after primary resection. In cases of liver metastasis, the mean disease free interval of resectable cases was longer than unresectable cases, and incidence of Dukes'A and B and normal preoperative CEA level were high in resectable cases. So in these cases, is may be important to make follow especially over two years after the original operation.
日本大腸肛門病学会の論文

Studies on Recurrence of Colorectal Cancer. Analysis of Clinical Factors Influencing on Disease Free Interval.:Analysis of Clinical Factors Influencing on Disease Free Interval

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