小児結腸癌の1例とその予後因子について

概要

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A 15-year-old boy was admitted to our hospital presenting with consistent abdominal pain and intestinal obstruction. He was diagnosed as having descending colon carcinoma and operated after decompression with long intestinal tube. Spreadings of cancer to the whole abdominal cavity was remarkable, and adjacent organs were involved locally. The tumor could not be resected. Histological diagnosis was mucin-producing adenocarcinoma and the patient died 5 months later. <BR>According to the analysis of 49 cases on primary carcinoma of the colon in children under 15 years of age, reported in Japanese literatures including this case, it showed that adolescent boys and the cases of cancer in transverse colon have poor risk factors and most of the cases who had these factors are stage IV-V. Patients who visited to hospital because of bloody stool and were diagnosed colon cancer preoperatively showed relatively long term survival. Patients of signet-ring cell carcinoma showed poor prognosis. However there is no difference on prognosis between mucinous carcinoma and adenocarcinoma, contrary to the preceding publications. <BR>This analysis indicates that early diagnosis and adequate surgical removal could improve the prognosis of the disease in children.