Possible Gliclazide-Induced Water Retention with Azotemia

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概要

• 論文の詳細を見る

• An 80-year-old woman with diabetes mellitus was treated with gliclazide. Prior to the gliclazide administration, her urinary excretion of albumin, serum urea nitrogen and serum creatinine were normal. After the medication, oliguria, edema and azotemia developed. On the twenty-fourth day when the edema was severe and generalized, gliclazide administration was terminated. On the following day urinary volume increased suddenly (5, 740 ml/day). Polyuria persisted for five days. Edema improved and urea nitrogen and creatinine were normalized thereafter. Though the mechanism is not known, the clinical course suggests that gliclazide is the principal causative factor in the water retention and azotemia in this patient.(Internal Medicine 33: 163-164, 1994)

著者

• Sakata Shigeki

  The Third Department Of Internal Medicine Gifu University School Of Medicine.

• Kamikubo Keita

  The Department Of Internal Medicine Takayama Red Cross Hospital

• SUGIYAMA Akihiko

  The Department of Internal Medicine, Takayama Red Cross Hospital

• TAKAMI Rieko

  The Department of Internal Medicine, Takayama Red Cross Hospital

• SUWA Tetsuya

  The Department of Internal Medicine, Takayama Red Cross Hospital

• HORIBE Nagatoshi

  The Department of Internal Medicine, Takayama Red Cross Hospital

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• A Case of Papillary Carcinoma of the Thyroid Associated with Parathyroid Adenoma without Hyperparathyroidism
• Possible Gliclazide-Induced Water Retention with Azotemia
• Autoimmune Hepatitis and Hypothyroidism Associated with Anti-thyroid Hormone Autoantibodies.
• Two Cases of Hashimoto's Thyroiditis with Transient Hypothyroidism.

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