Autoimmune Hepatitis and Hypothyroidism Associated with Anti-thyroid Hormone Autoantibodies.
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概要
- 論文の詳細を見る
A 40-year-old hypothyroid female who had been treated with synthetic thyroxine was admitted to our hospital in October 1988 due to abnormal liver function tests. She had low serum free triiodothyronine (T3; 2.3pg/ml) and high serum thyrotropin (TSH; 20.8 /μU/ml) concentrations. On the other hand, the serum free thyroxine (FT4) level was inappropriately high, being 2.46 ng/dl. Immune precipitation of radiolabeled thyroid hormones with her serum disclosed the binding of 125I-T3 and 125I-T4 to the extent of 9.5% and 11.3%, respectively (normal ranges for 125I-T3 and 125I-T4 binding are less than 6.3% and 5.9%, respectively). 125I-T4 binding to the patient's serum gamma globulin was completely displaced with the addition of unlabeled T4. Further examination disclosed that anti-T4 antibodies in her serum belong to IgG κ class immunoglobulin.(Internal Medicine 32: 21-25, 1993)
- 社団法人 日本内科学会の論文
著者
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Sakata Shigeki
The Third Department Of Internal Medicine Gifu University School Of Medicine.
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NAGAI Kotaro
the Department of Internal Medicine, Takayama Red Cross Hospital
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SARUI Hiroshi
the Department of Internal Medicine, Takayama Red Cross Hospital
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KAMETANI Masaaki
the Department of Internal Medicine, Takayama Red Cross Hospital
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OGAWA Toru
the Third Department of Internal Medicine, Gifu University School of Medicine
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TOKIMITSU Naoki
the Department of Internal Medicine, Takayama Red Cross Hospital
関連論文
- Renal Refractoriness to Phosphaturic Action of Parathyroid Hormone in a Patient with Hypomagnesemia
- A Case of Papillary Carcinoma of the Thyroid Associated with Parathyroid Adenoma without Hyperparathyroidism
- Possible Gliclazide-Induced Water Retention with Azotemia
- Autoimmune Hepatitis and Hypothyroidism Associated with Anti-thyroid Hormone Autoantibodies.
- Two Cases of Hashimoto's Thyroiditis with Transient Hypothyroidism.