Splenic Lymphoma with Villous Lymphocytes with CD5+, CDllc+ B-Cell Phenotype

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概要

• 論文の詳細を見る

• A 64-year-old male suffered from splenomegaly without lymphadenopathy. His WBC count on admission was 6.1×l09/l with 55% abnormal lymphocytes. No monoclonal gammopathy was detected. Abnormal cells shown in films usually had relatively abundant cytoplasm with serrated edges. Under phase-contrast microscopy, the cells displayed short, needle-like processes. The immunophenotype of peripheral blood mononuclear cells were CD19+, CD20+, CDllc+, FMC7+, CD5+, CD10-, CD25- and SIg+. The spleen histology showed a distinctive pattern of white pulp infiltration by abnormal lymphocytes with features of plasma cell differentiation. These findings were compatible with the features of splenic lymphoma with villous lymphocytes.(Internal Medicine 32: 472-475, 1993)

著者

• TSUCHIYA Jun

  College of Medical Care and Technology Gunma University

• MACHII Takashi

  the Division of Internal Medicine, Department of Clinical Research, Research Institute for Microbial Diseases, Osaka University

• KITANI Teruo

  the Division of Internal Medicine, Department of Clinical Research, Research Institute for Microbial Diseases, Osaka University

• YASHIRO Kunihiko

  the Department of Internal Medicine, Saiseikai Maebashi Hospital

• TSUCHIYA Jun

  College of Medical Care and Technology, Gunma University

• KASHIWABARA Kenji

  the 2nd Department of Pathology, Gunma University School of Medicine

• SAKURA Toru

  the Department of Internal Medicine, Saiseikai Maebashi Hospital

• MIYAWAKI Shuichi

  the Department of Internal Medicine, Saiseikai Maebashi Hospital

• HIRABAYASHI Hisami

  the Department of Internal Medicine, Saiseikai Maebashi Hospital

• SHIOZAKI Hiroko

  the Department of Internal Medicine, Saiseikai Maebashi Hospital

• MURAKAMI Hirokazu

  the 3rd Department of Internal Medicine, GunmaUniversity School of Medicine

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