A HTLV-I Carrier Who Showed Various Symptoms and Antibodies of Autoimmune Diseases.
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概要
- 論文の詳細を見る
We report a 37-year-old female HTLV-I carrier with complicating primary biliary cirrhosis (PBC) and mixed connective tissue disease (MCTD). Serum anti-HTLV-I antibody titer was ×256. Flower cells (4.5%) were found in the peripheral blood. Southern blot analysis showed no clonal integration in peripheral blood lymphocyte (PBL) DNA. Polymerase chain reaction showed the HTLV-I genome in PBLDNA. As cholestatic liver dysfunction and serum titer of anti-mitochondrial antibody were found, a clinical diagnosis of PBC was made. This patient later developed MCTD. These diseases responded well to prednisone. The pathogenetic relationship of HTLV-I infection with various autoimmune diseases is discussed.(Internal Medicine 32: 449-454, 1993)
- 社団法人 日本内科学会の論文
著者
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MIZUKI Masao
the Division of Internal Medicine, Department of Clinical Research, Research Institute for Microbial Diseases, Osaka University
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HASHIMOTO Mitsuo
the Renal Transplantation Center, Hyogo Prefectural Nishinomiya Hospital
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TAGAWA Shinichi
the Division of Internal Medicine, Department of Clinical Research, Research Institute for Microbial Diseases, Osaka University
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SHIBANO Masaru
the Division of Internal Medicine, Department of Clinical Research, Research Institute for Microbial Diseases, Osaka University
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OKAMOTO Yuji
the Division of Internal Medicine, Department of Clinical Research, Research Institute for Microbial Diseases, Osaka University
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NOJIMA Junzo
the Division of Internal Medicine, Department of Clinical Research, Research Institute for Microbial Diseases, Osaka University
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SAKATA Kenmei
the 2nd Department of Internal Medicine, Kumamoto University Medical School
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TAKATSUKI Kiyoshi
the 2nd Department of Internal Medicine, Kumamoto University Medical School
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KAWATA Sumio
the 2nd Department of Intenal Medicine, Osaka University Medical School
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HASHIMOTO Kozo
Japan Clinical Laboratories, LTD.
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ONOI Yutaka
the Division of Internal Medicine, Department of Clinical Research, Research Institute for Microbial Diseases, Osaka University
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MACHII Takashi
the Division of Internal Medicine, Department of Clinical Research, Research Institute for Microbial Diseases, Osaka University
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KITANI Teruo
the Division of Internal Medicine, Department of Clinical Research, Research Institute for Microbial Diseases, Osaka University
関連論文
- Splenic Lymphoma with Villous Lymphocytes with CD5+, CDllc+ B-Cell Phenotype
- A HTLV-I Carrier Who Showed Various Symptoms and Antibodies of Autoimmune Diseases.