Interleukin-6-producing Thymic Squamous Cell Carcinoma Associated with Castleman's Disease and Nephrotic Syndrome
スポンサーリンク
概要
- 論文の詳細を見る
When a 63-year-old man was hospitalized with nephrotic syndrome due to focal segmental glomerulosclerosis, a mediastinal mass was discovered. A biopsy specimen obtained by mediastinoscopy showed findings compatible with the plasma cell type of Castlemans disease. Fever, anemia, and anti-nuclear antibody were present. Serum concentrations of gamma globulin, acute phase proteins, and, most strikingly, interleukin-6 (IL-6) were elevated. Methylprednisolone pulse therapy resulted in no clinical improvement. Pathologic examination of the resected thymic tumor showed a squamous cell carcinoma immunoreactive for IL6. To our knowledge, this case represents the first reported IL-6-producing thymic squamous cell carcinoma associated with Castlemans disease and nephrotic syndrome.(Internal Medicine 41: 871-874, 2002)
- 社団法人 日本内科学会の論文
- 2002-10-01
著者
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Uramoto Hiroki
Department Of Cardiology Hirai Hospital
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Uramoto Hiroki
Department Of Internal Medicine Nara Prefectural Mimuro Hospital
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MATSUMURA Norihiko
Department of Internal Medicine, Nara Prefectural Mimuro Hospital
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Nonaka Hideo
Department Of Internal Medicine Nara Prefectural Mimuro Hospital
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Nonaka Hideo
Department Of Intemal Medicine Nara Prefectural Mimuro Hospital
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Saito Naotoshi
Department Of Internal Medicine Nara Prefectural Mimuro Hospital
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Shiiki Hideo
Department Of Internal Medicine Nara Medical University
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Shiiki Hideo
Department Of Internal Medicine Division Of Nephrology And Rheumatology Aichi Medical University Sch
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Nakamura Shinobu
Department Of General Medicine And Clinical Investigation Nara Medical University
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Hanatani Masakazu
Department Of Internal Medicine Nara Prefectural Mimuro Hospital
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Matsumura Norihiko
Department Of Internal Medicine Nara Prefectural Mimuro Hospital
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NAKAMURA Shinobu
Department of Biological Science, Faculty of Science, Kumamoto University
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