An Autopsy Case of Hypertrophic Cardiomyopathy with Pathological Findings Suggesting Chronic Myocarditis.
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概要
- 論文の詳細を見る
Myocardial fibrosis in patients with hypertrophic cardiomyopathy (HCM) may play an important role in the function and/or dimensions of the left ventricle. We present an autopsied case of HCM followed for 10 years. A 68-year-woman with HCM underwent trans-aortic myectomy of the interventricular septum in 1979. A significant amount of round cell infiltration, myocardial fibrosis and disarray were observed in the resected specimen. She experienced repeated admissions due to diabetes mellitus and congestive heart failure, and died of renal failure in 1989. An autopsy revealed extensive myocardial fibrosis and significant cell infiltration in the ventricular myocardium. The infiltrating cells were almost all lymphocytes, and the ratio of CD4 to CD8 was 3.8. This ratio was different from that of typical viral myocarditis. This case suggests that there may be an undefined inflammatory process causing fibrosis in HCM, in addition to the ischemia due to intramural small coronary artery stenosis.
- International Heart Journal刊行会の論文
著者
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Kawai Sachio
Research Laboratory for Cardiovascular Pathology, Juntendo University School of Medicine
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Okada Ryozo
Research Laboratory for Cardiovascular Pathology, Juntendo University School of Medicine
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Kawano Hiroaki
Research Laboratory For Cardiovascular Pathology Juntendo University School Of Medicine
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Inagaki Yoshiaki
Third Department Internal Medicine Chiba University
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Nishijo Takashi
Division Of Cardiology Dept. Of Int. Med. School Of Med. Juntendo Univ.
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Shirai Toshikazu
Department Of Pathology Juntendo University School Of Medicine
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Kawai Sachio
Research Laboratory For Cardiovascular Pathology Department Of Internal Medicine Juntendo University
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Okada Ryozo
Research Laboratory For Cardiovascular Pathology Division Of Cardiology Department Of Internal Medic
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Kawano Hiroaki
Research Laboratory for Cardiovascular Pathology, Juntendo University School of Medicine
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KAWANO Hiroaki
Research Laboratory for Cardiovascular Pathology
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NISHIJO Takashi
Division of Cardiology, Department of Internal Medicine, Juntendo University School of Medicine
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OKADA Ryozo
Research Laboratory for Cardiovascular Pathology
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