Reversal of rest asynergy during exercise in patients with coronary artery disease.

スポンサーリンク

概要

• 論文の詳細を見る

• The diagnosis of ischemic heart disease by radionuclide ventriculography (RNV) is performed on the basis of an abnormal response of the left ventricular ejection fraction and the occurrence, or aggravation, of regional wall motion abnormality during exercise. However, the abnormal wall motion observed by RNV at rest is improved in some patients with coronary artery disease during exercise. We examined the clinical features of such patients who showed a paradoxical response of regional wall motion. The left ventricle was divided into 4 segments: anteroseptal, apical, inferior and posterolateral. The degree of wall motion of each segment was classified into 5 grades and scored according to a 5 point system: 4=normokinesis, 3=hypokinesis, 2=severe hypokinesis, 1=akinesis and 0=dyskinesis. The wall motion score (WMS) was calculated as the sum of each segment score. If the WMS increased by 2 points or more during exercise, the case was defined as having shown significant improvement of wall motion.Improvement in WMS was found in 26 (12%) of 209 serial patients who underwent exercise RNV, exercise thallium myocardial scintigraphy and coronary angiography. Clinically, half of these patients had a variant form of angina pectoris. With respect to coronary lesions in the segments with reversible asynergy, 12 patients had 0 vessel disease, 8 had lesions with stenosis of less than 75% and 3 showed an adequate collateral circulation. Redistribution found on the exercise thallium myocardial scintigram at the same sites of improved wall motion was identified in only 1 patient. An analysis of patients with paradoxical improvement of wall motion during exercise suggests the involvement of coronary spasm, an improvement of coronary flow reserve, such as could be produced by regression or recanalization of the main lesions, or establishment of significant collateral circulation.

• International Heart Journal刊行会の論文

著者

• Futagami Yasuo

  First Department of internal Medicine, Mie University School of Medicine

• Aoki Toshikazu

  First Department Of Internal Medicine Mie University

• Konishi Tokuji

  First Department Of Internal Medicine Faculty Of Medicine Mie University

• Nakano Takeshi

  First Dep. Of Int. Med. Mie Univ. School Of Med. Tsu Mie

• WATANABE Kazumi

  Second Department of Internal Medicine, Shiohama Prefectural Hospital

• YAMAMURO Masashi

  Second Department of Internal Medicine, Shiohama Prefectural Hospital

• AOKI Toshikazu

  First Department of Internal Medicine, Mie University School of Medicine

• KOYAMA Takao

  First Department of Internal Medicine, Mie University School of Medicine

関連論文

• Correlation Between Late Gadolinium Enhancement and Diastolic Function in Hypertrophic Cardiomyopathy Assessed by Magnetic Resonance Imaging
• OJ-287 The Role of Loading Sequence on Left Ventricular Relaxation in Patients with Diastolic Heart Failure in the Presence of Hypertension(Heart failure, clinical-5 (M) OJ48,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of t
• Intravascular Hemolysis in Aortic Stenosis
• RETROPERITONEAL PERFORATION OF A PANCREATIC CYST DURING ENDOSCOPIC RETROGRADE PANCREATOGRAPHY
• PJ-706 Inferior Vena Cava Filters Reduce the Incidence of Acute Deterioration in Patients with Acute Pulmonary Embolism(Pulmonary circulation-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-797 Out-of-hospital Cases with Acute Pulmonary Embolism after the Mid Niigata Prefecture Earthquake(Pulmonary circulation-4 (H) PJ140,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Clinical Characteristics, Diagnosis and Management of Patients With Pulmonary Thromboembolism Who are Not Diagnosed in the Acute Phase and Not Classified as Chronic Thromboembolic Pulmonary Hypertension
• Inferior Vena Cava Filter is a New Additional Therapeutic Option to Reduce Mortality From Acute Pulmonary Embolism
• Venous Thromboembolism : Deep Vein Thrombosis With Pulmonary Embolism, Deep Vein Thrombosis Alone, and Pulmonary Embolism Alone(Hypertension/Pulmonary Circulation)
• PJ-743 Incidence and Clinical Characteristics of Venous Thromboembolism(Pulmonary circulation(04)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• OE-114 Incidence of Pulmonary Embolism in Psychiatric Wards in Japan(Thromboembolism/Antithrombotic therapy/Thrombolysis(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Pulmonary embolism is an important cause of death in young adults
• Unusual Pulmonary Embolism : Septic Pulmonary Embolism and Amniotic Fluid Embolism
• PJ-708 Pulmonary Embolism is an Important Cause of Death in Young Adult(Pulmonary circulation-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Cancer and Pulmonary Embolism : Thrombotic Embolism, Tumor Embolism, and Tumor Invasion Into a Large Vein(Clinical Investigation)
• An Analysis of Pulmonary Embolism Associated with Pregnancy, Deliverly and Infection in 396, 982 Autopsies(Thrombosis/Thrombolysis 3 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Identification of novel hepatitis C virus-specific cytotoxic T lymphocyte epiotpe in NS3 region
• The emerging role of caspase inhibitors in gastrointestinal cancers
• Septic endophthalmitis and meningitis associated with Klebsiella pneumoniae liver abscess
• Primary Localized Amyloidosis of the Small Intestine Presenting as an Intestinal Pseudo-obstruction : Report of a Case
• 29) ^201 TI MYOCARDIAL SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY IN PATIENTS WITH DILATED CARDIOMYOPATHY
• ASSESSMENT OF LEFT VENTRICULAR REGIONAL WALL MOTION ABNORMALITIES WITH GATED BLOOD POOL SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY : Imaging Techniques : FREE COMMUNICATIONS (II) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULAT
• SEVERE SEGMENTAL WALL MOTION ABNORMALITIES IN DILATED CARDIOMYOPATHY : A COMMON BUT POOR PROGNOSTIC SIGN : Imaging Techniques : FREE COMMUNICATIONS (II) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• CHANGE OF EJECTION FRACTION DURING EXERCISE IN PATIENTS WITH CORONARY ARTERY DISEASE : MULTIVARIABLE ANALYSIS : Nuclear Cardiology (I) : FREE COMMUNICATIONS (I) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• EVALUATION OF WALL THICKNESS IN HYPERTROPHIC CARDIOMYOPATHY, USING ECG-GATED Tl-201 MYOCARDIAL SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Radioisotope
• EVALUATION OF LEFT VENTRICULAR FUNCTION BY MULTISTAGE EXERCISE USING GATED BLOOD POOL SCINTIGRAPHY : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Radioisotope
• VENTRICULAR CONTRACTION ABNORMALITIES IN WPW SYNDROME AND VARIOUS CONDUCTION DISORDERS : ASSESSMENT WITH RADIONUCLIDE PHASE ANALYSIS : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Radioisotope
• PE-286 Curative Ablation of Local Electrocardiogram with Delayed Components during Sinus Rhythm or Right Ventricular Pacing in Scar Left Ventricular Tachycardia(Arrhythmia, therapy-13, The 71st Annual Scientific Meeting of the Japanese Circulation Society
• ANGIOGRAPHIC STUDY OF CORONARY COLLATERALS IN INFARCTED PATIENTS : PROCEEDINGS OF THE 38TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
• CLINICAL STUDIES ON THE CORONARY CIRCULATION RE-EVALUATION OF CORONARY FLOW INDEX BY SELECTIVE CORONARY ANGIOGRAPHY : PROCEEDINGS OF THE 38TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
• Osteodystrophy in patients with chronic hepatitis and liver cirrhosis
• POSTEXTRASYSTOLIC RELAXATION IN VARIOUS HEART DISEASES : Ventricular Function : 46th Annual Scientific Meeting, Japanese Circulation Society
• PJ-798 Randomized Comparison of Ticlopidine versus Cilostazol for Antiplatelet Therapy after Sirolimus-Eluting Stent Implantation(Thromboembolism/Antithrombotic therapy/Thrombolysis-5 (H) PJ141,Poster Session (Japanese),The 70th Anniversary Annual Scienti
• PJ-775 Constrictive Remodeling of Coronary Artery Accompany with the Progression of Diabetic Nephropathy(Intravascular endoscopy/Intravascular ultrasound-7 (I) PJ135,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese
• The Availability of D-dimer Test by Latex Photometric Immunoassay Even for Isolated Calf Deep Vein Thrombosis(Pulmonary Circulation 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• H-FABP Elevation is Associated with Right Ventricular Dysfunction in Acute Pulmonary Thromboembolism(Pulmonary Circulation 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PE-433 Long term efficacy of combination therapy with sildenafil and beraprost for primary pulmonary hypertension(Pulmonary Circulation 3 (H) : PE74)(Poster Session (English))
• PE-051 A Comparative Effect of Various Mechanical Prophylactic Methods for the Prevention of Venous Thromboembolism(Thromboembolism/Thrombolysis 1 (IHD) : PE9)(Poster Session (English))
• OJ-437 Comparison between Sildenafil and Beraprost Sodium in Patients with Pulmonary Hypertension(Pulmonary Circulation 1 (H) : OJ53)(Oral Presentation (Japanese))
• Clinical feasibility and effectiveness of retrievable inferior vena cava filter : Gunther tulip filter
• MYPT2 Functions as a Regulatory Subunit of Cardiac MP, which Modulates Ca^ Sensitization of Contraction and LV Function in vivo(Gene Therapy/Genetic Engineering (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Critical Role of Rho/Rho-kinase Pathway for C-reactive Protein-induced Plasminogen Activator Inhibitor-1 Expression in Bovine Aortic Endothelial Cells(Atherosclerosis, Basic 1 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-075 Cardiac Myosin Phosphatase Could Modulate LV Function(Genetics/Genetically Engineered Models 1 (H) : PJ13)(Poster Session (Japanese))
• Aorto-Coronary Dissection During Angioplasty in a Patient With Myxedema
• Acute Myocardial Infarction in a Patient With Anomalous Left Coronary Artery Origin and Primary Antiphospholipid Syndrome
• Unique Myocardial Fibrosis Pattern by Late Gadolinium Enhanced Magnetic Resonance Imaging in a Patient With Isolated Noncompaction of the Ventricular Myocardium
• PJ-066 Cardiac Magnetic Resonance Imaging can Reveal a Variety of Myocardial Damage in Patients with Takotsubo Cardiomyopathy(PJ011,CT/MRI (Myocardium) 4 (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• An autopsy case of a malignant pericardial mesothelioma in a Japanese young man
• Level of Plasma Tissue Factor Pathway Inhibitor is Inversely Correlated With Intraarterial Diastolic Pressure in Subjects Who Underwent Coronary Angiography
• Rhabdomyolysis and Myocardial Damage Induced by Palytoxin, a Toxin of Blue Humphead Parrotfish
• THE STRUCTURE AND THE TISSUE DISTRIBUTION OF MYOSIN-BOUND PHOSPHATASE, A NEW REGULATORY PROTEIN OF VASCULAR TONE
• EXPERIMENTAL ANALYSIS OF REGIONAL WALL MOTION IN THE RIGHT VENTRICLE : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Ventricular Function (I)
• Difference in the Incidence of Cough Induced by Angiotensin Converting Enzyme Inhibitors: a Comparative Study Using Imidapril Hydrochloride and Enalapril Maleate
• EFFICACY OF RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR IN PULMONARY THROMBOEMBOLISM : MULTI-CENTER TRIAL (PHASE II) : Myocardial Metabolism, Biochemistry : 53 Annual Scientific Meeting, Japanese Circulation Society
• OJ-142 Serum Intact Parathyroid Hormone levels can predict hospitalization for heart failure(Heart failure, clinical(05)(M),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Impact of Nicorandil to Prevent Reperfusion Injury in Patients With Acute Myocardial Infarction : Sigmart Multicenter Angioplasty Revascularization Trial (SMART)
• OE-108 Left Ventricular Radial Eccentricity Induces Wall Motion Dyssynchrony in Patients with Pulmonary Hypertension(Echo/Doppler-1 (I) OE18,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Infected Papillary Fibroelastoma Attached to the Atrial Septum
• The act of defecation or micturition may trigger the development of acute thromboembolism for inpatients
• Plasma troponin-T as a marker for myocardial injury is increased by right ventricular overload in patients with acute pulmonary thromboembolism
• 15) CLINICOPATHOLOGICAL STUDY IN 23 PATIENTS WITH CARDIAC AMYLOIDOSIS
• 15) EXERCISE RI ANGIOGRAPHY IN PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY : EVALUATION OF LEFT VENTRICULAR FUNCTION WITH TEMPORAL FOURIER ANALYSIS
• -0053-IS NITROGLYCERIN (NTG) EXERCISE TEST USEFULL FOR DETECTING ISCHEMIC HEART DISEASE
• PJ-415 Cardiac Resynchronization is Kept Going Immediately after Interrupting Bi-ventricular Pacing Only in the Responders(Heart failure, clinical-13 (M) PJ70,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circula
• FRS-081 Activation of Small G protein RhoA Is Essential for Branching Morphogenesis in Endothelial Cell through Rho-kinase Independent Pathway.(NO and Cardiovascular System (H) : FRS10)(Featured Research Session (English))
• RhoA Activation in Vascular Smooth Muscle Cells from Stroke-Prone Spontaneously Hypertensive Rats
• Liver cirrhosis with synchronous gas gangrene and spontaneous bacterial peritonitis due to E. coli
• Asymptomatic primary pulmonary hypertension associated with liver cirrhosis
• Multiple Pulmonary Emboli With Pulmonary Hypertension Caused by Effort Thrombosis and Effective Balloon Venoplasty of the Subclavian Vein
• Parallel recording of physical activity on commercial Holter recorders
• High speed detection of R-R intervals for universal Holter recordings
• DOES HYPERTENSION OR AGING MODULATE DIRECTIONAL SHORTENING OF THE LEFT VENTRICULAR MIDWALL?
• INDENTIFICATION AND CHARACTTERIZATION OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE(PDE)IN HUMAN HEART AND THE PDE INHIBITORS AS CARDIOTONIC AGENTS
• -184-EFFECTS OF AMRINONE AND ENOXIMONE ON THE SUBCLASSES OF CYCLIC AMP PHOSPHO-DIESTERASE FROM HUMAN HEART : Cardiac Metabolism, Cardiac Biochemistry : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION
• Myocardial viability assessed by dobutamine stress and Gd-DTPA contrast enhanced magnetic resonance imaging in acute myocardial infarction
• Natural History and Prognosis of Ischemic Heart Disease : Medical and Surgical Aspects of Treatment of "High Risk" Cardiovascular Diseases
• A mechanism of phorbol 12, 13-dibutylate induced smooth muscle contraction without change in intracellular free-Ca^ concentration
• Ca^-DEPENDENT AND Ca^-INDEPENDENT VASCULAR SMOOTH MUSCLE RELAXATION INDUCED BY CARDIOTONIC AGENTS THAT BELONG TO A GROUP OF PHOSPHODIESTERASE INHIBITORS
• Activation of RhoA Is Responsible for Hypertension
• The Relationship between the Repolarization Dispersion from the 12-Lead Surface ECG and the Arrhythmogenecity of Takotsubo Cardiomyopathy
• Shortening of Conduction Time Over Arborized Atrioventricular Accessory Pathway With Mahaim Fibers Physiology Just Before Interruption During Radiofrequency Ablation
• Relationship Between Left Ventricular Diastolic Function at Rest and Exercise Capacity ira Patients who Have Suffered a Previous Myocardial Infarction
• 5 Assessment of coronary heart disease with cardiac magnetic resonance imaging(Plenary Session 6 (PL6) (I) : Role of Diagnostic Imaging in the Management of Coronary Artery Disease and Its Cost Effectiveness)(Special Program)
• Pulmonary Aspergillus niger
• Prevalence and Signal Characteristics of Late Gadolinium Enhancement on Contrast-Enhanced Magnetic Resonance Imaging in Patients With Takotsubo Cardiomyopathy
• Cholesterol Crystal Embolization (CCE) after Cardiac Catheterization: A Case Report and a Review of 36 Cases in the Japanese Literature:A Case Report and a Review of 36 Cases in the Japanese Literature
• Intraortic Pulse Pressure Is Correlated With Coronary Artery Stenosis
• Sudden death during ambulatory monitoring in a patient with left main coronary artery disease.
• Evaluation of Aortic Regurgitation Using Cine Magnetic Resonance Imaging.
• Cardiac tamponade in rheumatoid arthritis. Successful treatment with intrapericardial steroid administration.:Successful Treatment with Intrapericardial Steroid Administration
• Alternans Decay of Postextrasystolic Potentiation in Human Left Ventricle
• Reversal of rest asynergy during exercise in patients with coronary artery disease.

もっと見る 閉じる

スポンサーリンク