Prominent negative u wave in variant angina pectoris.
スポンサーリンク
概要
- 論文の詳細を見る
The extremely prominent negative U wave occasionally appears during a cardiac attack in variant angina pectoris. The clinical profile of the negative U wave was therefore studied in 80 patients with variant angina pectoris (VA) and 33 controls with resting angina pectoris (RA). The prominent negative U wave appeared in 55 of the patients with VA (68.8% of patients) and in 10 of the patients with RA (30.3%); thus, there was a significant difference in the appearance of the wave between the 2 groups of patients (p<0.001). The leads in which the negative U wave appeared were mostly consistent with those in which the ST segment was elevated. The negative U wave began to appear at about the time when ST-segment elevation began to improve; the wave then gradually became very prominent and then eventually disappeared. The patients with VA and also those with RA on whose ECGs the negative U wave appeared during exercise testing also had negative U waves during spontaneous episodes of angina. An investigation of the frequency of appearance of ST deviation and negative U waves during exercise testing, regardless of the type of angina pectoris, disclosed that the negative U wave appeared in 14 of 20 patients with ST-segment elevation (70% of patients), while the negative U wave appeared in only 52 of 519 patients with either no ST change or ST-segment depression (10.4%); thus, there was a significant difference in the appearance of the negative U wave between these 2 groups (p<0.001). Coronary cinearteriography failed to disclose any apparent difference between the appearance of the negative U wave and the presence of stenosis. The prognosis of VA and RA in patients with negative U waves was less favorable compared to those without negative U waves. In particular, we noted that of the 10 patients with RA associated with negative U waves, 4 died. Although the mechanism of the negative U wave is not yet known, we believe that the above findings contribute to its elucidation.
- International Heart Journal刊行会の論文
著者
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Hata Noritake
Department Of Intensive Care Unit Chiba-hokusoh Hospital Nippon Medical School
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Kusama Yoshiki
Department Of Internal Medicine And Cardiology Nippon Medical School Tama-nagayama Hospital
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Otsu Fumio
Department Of Internal Medicine Nippon Medical School
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IIDA NOBUKO
Department of Internal Medicine, Nippon Medical School
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Suzuki Kengo
Department Of Applied Bioscience And Biotechnology Faculty Of Life And Environmental Science
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Nejima Jun
Department Of Intensive Care Medicine Nippon Medical School
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Kishida Hiroshi
Department Of Cardiology Nippon Medical School
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Saito Tsutomu
Department Of Applied Physics Faculty Of Engineering Tohoku University
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Suzuki Takeshi
Department Of Allergy And Rheumatology Graduate School Of Medicine University Of Tokyo
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SUZUKI Kengo
Department of Internal Medicine, Nippon Medical School
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