Cardiac death and myocardial lesions in non-stroke SHRSP under specific pathogen-free system.

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概要

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• The most remarkable finding in SHRSP with cardiac death under specific pathogen-free system was idiopathic diffuse fatty degeneration of the myocardium.Besides fatty degeneration, diffuse myocardial fibrosis and scattered infarction were observed. In male rats the incidence of cardiac death increased with each generation. Therefore, this myocardial degeneration seemed to be hereditary disorder. The SHRSP with cardiac death seemed to be a new type of SHR, namely Heart-Prone SHR (SHRHP). SHRHP may be a kind of animal model for congestive cardiomyopathy (COCM) in human beings.

• International Heart Journal刊行会の論文

著者

• Saito Naohiro

  Kowa Tokyo Instit.

• Miyazaki Tadahiko

  Clinical Research Division of Central Hospital of J. N. R.

• Ueda Hideo

  Clinical Research Division of Central Hospital of J. N. R.

• Suganuma Yoshio

  Kowa Tokyo Instit.

• KATO Yasushi

  Kowa Tokyo Institute, Central Hospital of J.N.R.

• Suganuma Yoshio

  Kowa Co. Tokyo Research Laboratory

関連論文

• PATTERN OF HYPERTENSION, LIFE SPAN AND CARDIORENAL PATHOLOGY IN SHRSP UNDER THE SPECIFIC PATHOGEN FREE SYSTEM : Hypertension I : Ist Auditorium : Proceedings of the 43rd Annual Meeting of the Japanese Circulation Society, Tokyo, 1979
• MYOCARDIAL LESIONS IN STROKE-PRONE SHR REVEALED FAMILIAL AGGREGATION OF CONGESTIVE HEART FAILURE UNDER SPECIFIC PATHOGEN FREE SYSTEM : Cardiomyopathy : FREE COMMUNICATIONS (Abstract) : 45 Annual Scientific Meeting, Japanese Circulation Society
• Cardiac death and myocardial lesions in non-stroke SHRSP under specific pathogen-free system.
• The Effect of Salt on SHR, especially on Heartfailure-Prone SHR (SHRHP)
• The Blood Pressure, Life Span, Body Weight in Both Sexes of SHRSP during 55 Weeks under Specific Pathogen Free System
• The Heart Failure and Myocardial Changes of SHRSP derived from Non-stroke Parents under Specific Pathogen-free System
• Effects of Salt and Beta-Blocker (Nipradilol and Propranolol) on Blood Pressure and Renal Histology of SHR (SHRSR, SHRSP and SHRHP)
• The Biochemical and Hematological Changes of Blood in SHR and the Effects of Different Kinds of Diets upon Those Findings

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