Antihypertensive Effect of 4 (-2-Nitrophenyl)-2, 6-Dimethyl-1, 4-Dihydropyridine-3, 5-Dicarbonic Acid Dimethylester (Nifedipine, Bay-a 1040), a New Coronary Dilator

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概要

• 論文の詳細を見る

• Oral administration of 10mg. of Bay-a 1040, a new coronary dilator, produced a marked reduction of arterial pressure which was associated with a consistent decrease in peripheral vascular resistance and an increase in cardiac output and stroke volume. Changes in heart rate and left ventricular work were variable. In 20 hypertensive patients treated with the drug in doses of 10mg. per day, a modest antihypertensive effect was achieved. Side effects including dryness of the mouth and burning sensation in face and legs, were observed in few patients.

• International Heart Journal刊行会の論文

著者

• Murakami Mototaka

  Dept. Of 1st Pathology School Of Medicine Kanazawa University

• MURAKAMI Mototaka

  Second Department of Medicine, Kanazawa University

• MURAKAMI Eiji

  Second Department of Medicine, Kanazawa University

• TAKEKOSHI Noboru

  Second Department of Medicine, Kanazawa University

• TSUCHIYA Masayuki

  Second Department of Medicine, Kanazawa University

• KIN Takeo

  Second Department of Medicine, Kanazawa University

• ONOE Tamehisa

  Second Department of Medicine, Kanazawa University

• TAKEUCHI Nobuo

  Second Department of Medicine, Kanazawa University

• FUNATSU Toshiro

  Second Department of Medicine, Kanazawa University

• HARA Shigeki

  Second Department of Medicine, Kanazawa University

• ISHISE Shozo

  Second Department of Medicine, Kanazawa University

• MIFUNE Junichiro

  Second Department of Medicine, Kanazawa University

• MAEDA Masahiro

  Second Department of Medicine, Kanazawa University

• TAKEKOSHI Noboru

  Second Department of Internal Medicine, School of Medicine, Kanazawa University

• TSUCHIYA Masayuki

  Second Department of Internal Medicine, School of Medicine, Kanazawa University

• MURAKAMI Eiji

  Second Department of Internal Medicine, School of Medicine, Kanazawa University

• FUNATSU Toshiro

  Second Department of Internal Medicine, Kanazawa University

• MURAKAMI Mototaka

  Second Department of Internal Medicine, Kanazawa University School of Medicine

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