Blood Flow Velocity in the Carotid Artery as a Measure of Myocardial Contractility

概要

論文の詳細を見る
An attempt was made to derive a useful noninvasive index to evalute a change in myocardial contractile state using transcutaneous Doppler flow-velocity curve from the carotid artery.In 5 mongrel dogs and in 43 patients with various heart disease, Doppler flow velocity curves were obtained from the ascending aorta intravascularly using a Doppler catheter and/or from carotid artery transcutaneously using a Doppler probe. The first derivative of left ventricular pressure (dp/dt) and electrocardiogram (ECG) were recorded simultaneously. The following 3 indices were measured from the Doppler flow velocity curves: (1) maximum acceleration of blood flow (dv/dt), (2) time from onset of ejection to peak flow (time-to-peak), (3) time interval between the beginning of Q wave of ECG to the peak of Doppler flow velocity curve (ECG Q-Doppler peak). Among these 3 indices, only ECG Q-Doppler peak demonstrated a significant correlation between the values measured intravascularly and transcutaneously. Also, only ECG Q-Doppler peak showed significant correlation with maximum of dp/dt (max dp/dt).Since ECG Q-Doppler peak showed correlation with heart rate, the difference between observed and predicted ECG Q-Doppler peak (_??_ECG Q-Doppler peak) was calculated to exclude the effect of heart rate. Predicted value of ECG Q-Doppler peak was calculated from the regression equation between heart rate and ECG Q-Doppler peak in the separate experiments. There was a significant correlation between _??_ECG Q-Doppler peak and max dp/dt.In 15 patients with coronary artery disease and in 16 healthy subjects, _??_ECG Q-Doppler peak and the other noninvasive method (systolic time intervals) were measured. JECG Q-Doppler peak showed better result in the separation of 2 groups than by systolic time intervals. Itwas concluded that 4ECG Q-Doppler peak is a useful index to evaluate the myocardial contractile state since this index is readily obtained noninvasively.
International Heart Journal刊行会の論文

Blood Flow Velocity in the Carotid Artery as a Measure of Myocardial Contractility

スポンサーリンク

概要

著者

関連論文

スポンサーリンク