Electrophysiological Effects of Lidocaine in Sick Sinus Syndrome
スポンサーリンク
概要
- 論文の詳細を見る
Electrophysiological studies were performed to see the effects of lidocaine on the conduction system, particularly sinus node and atrium in 40 patients of SSS, using HBE recordings, rapid atrial pacing and atrial extrastimulus technique. Sinus cycle length, PA (PA), AH, HV intervals, calculated SACT, and refractory periods of atrium, AV node and His-Purkinje system did not change after lidocaine. Only maximum CSRT was significantly increased with lidocaine. These results were not affected by pretreatment of atropine.In conclusion, the combining rapid atrial pacing with lidocaine may be useful to manifest the masked sinus node abnormalities. It was suggested that lidocaine directly depressed sinus node automaticity in SSS patients, without affecting perinodal tissue. Therefore, lidocaine should be used with caution in patients with known or suspected SSS.
- International Heart Journal刊行会の論文
著者
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Miyoshi Akima
First Dep. Of Int. Med. Hiroshima University School Of Medicine
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Ishii Yukiko
The First Department Of Internal Medicine Hiroshima University School Of Medicine
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Fujitani Kazuhiro
First Department Of Internal Medicine Hyogo College Of Medicin
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Tateishi Hironobu
The Department Of Internal Medicine Hiroshima City Hospital Hiroshima Japan
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ISHII Yukiko
First Department of Internal Medicine, Hiroshima University School of Medicine
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MITSUDA Hiroki
First Department of Internal Medicine, Hiroshima University School of Medicine
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ENO Shin
First Department of Internal Medicine, Hiroshima University School of Medicine
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FUKUI Nobuyuki
First Department of Internal Medicine, Hiroshima University School of Medicine
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IWAMOTO Takashi
First Department of Internal Medicine, Hiroshima University School of Medicine
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FURUTA Yutaka
First Department of Internal Medicine, Hiroshima University School of Medicine
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YOSHIDA Masao
First Department of Internal Medicine, Hiroshima University School of Medicine
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SUZUKAWA Mutsuo
The Department of Internal Medicine, Hiroshima City Hospital
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MIYOSHI Akima
First Department of Internal Medicine, Hiroshima University School of Medicine
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TATEISHI Hironobu
The Department of Internal Medicine, Hiroshima City Hospital
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