神経終末膜とイオンのin vitroにおける相互作用

概要

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In comparison with other excitable membranes, interactions with some ions of synaptosomal membranes in vitro were dealt with in the present review. Effects of external high K+ on synaptosomal Ca2+-binding and on Ca2+-influx of synaptosomes were reviewed. External high K+ induced the swelling of synaptosomes. Such phenomena were discussed in connection with the liberation of membrane-bound Ca2+ From the changes in extrinsic fluorescence, K+-induced depolarization of synaptosomal membrane was described. Based on these results, some changes in membrane structure and/or its permeability properties accompanied with depolarization were discussed. In addition, using spin-labels, changes in fluidity of synaptosomal membranes induced some ions were also described.
日本生物物理学会の論文