アセチルコリンレセプタ-によるイオンの透過

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概要

• 論文の詳細を見る

• Acetylcholine induces both a fast conformational change of acetylcholine rece ptor that results in the opening of ion-conducting channels through the membrane, and a slow conformational change that results in an inactivation of the receptor (desensitization). The relationship between the binding of the agonist to the receptor and the receptor-mediated ion flux or the desensitization has been studied by three kinds of experiments; 1) ion flux measurements with a quench flow method, 2) fluorescence measurements with a stopped flow method and 3) α-toxin binding to the receptor. Several models are summarized and discussed.

• 日本生物物理学会の論文

著者

• 青島 均

  山口大学・教養部

関連論文

• マウスにおけるアルギニン・バソトシンレセプターの同定と分布(解剖学)
• アセチルコリンレセプタ-によるイオンの透過

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