A Case of Acquired Fanconi Syndrome Induced by Zoledronic Acid
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概要
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A 61-year-old woman with metastatic breast cancer was diagnosed as having acquired Fanconi syndrome. In this case, the cause of this syndrome was most likely zoledronic acid (Zometa®), which had been infused intravenously at a dose of 4 mg over 15 minutes weekly because of malignancy-associated hypercalcemia. Zoledronic acid is nephrotoxic and may induce severe tubular dysfunction, which can cause development of Fanconi syndrome. Therefore, close monitoring of proximal tubular function is recommended during therapy with zoledronic acid, especially when frequent administration of zoledronic acid is needed.
- 社団法人 日本内科学会の論文
著者
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Sakai Daisuke
Department Of Computer Science Kitami Institute Of Technology
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Imamura Fumio
Department Of Pathology Osaka Medical Center For Cancer And Cardiovascular Diseases
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Yagi Toshinari
Department Of Clinical Oncology Osaka Medical Center For Cancer And Cardiovascular Diseases
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Sugimoto Naotoshi
Department Of Clinical Oncology Osaka Medical Center For Cancer And Cardiovascular Diseases
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Yagi Toshinari
Department of Clinical Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Japan
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Yoshinami Tetsuhiro
Department of Clinical Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Japan
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Imamura Fumio
Department of Clinical Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Japan
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