Adalimumab-induced Interstitial Pneumonia with an Improvement of Pre-existing Rheumatoid Arthritis-associated Lung Involvement
スポンサーリンク
概要
- 論文の詳細を見る
A 78-year-old man with an 18-year history of rheumatoid arthritis (RA) was treated with tumor necrosis factor (TNF)-α inhibitor adalimumab. Chest computed tomography showed a previously detected consolidation. The patients arthritic symptoms substantially decreased with the initiation of adalimumab, with a simultaneous improvement of the lung lesion. However, additional interstitial pneumonia was found a month after starting adalimumab. This course suggested that adalimumab might be effective against RA-associated lung disease, but may also have caused drug-induced interstitial pneumonia. This is the first report indicating that TNF-α inhibitor shows simultaneously conflicting actions in a patient with RA-related lung disease.
著者
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Kadota Jun-ichi
Internal Medicine 2 Faculty Of Medicine Oita University
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Oka Hiroaki
Internal Medicine 2 Oita University Faculty Of Medicine
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Komiya Kosaku
Internal Medicine 2 Oita University Faculty Of Medicine
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Iwata Atsuko
Internal Medicine 2 Oita University Faculty Of Medicine
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Ishii Hiroshi
Internal Medicine 2 Oita University Faculty Of Medicine
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Iwata Atsuko
Internal Medicine 2, Oita University Faculty of Medicine, Japan
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Fujita Naoko
Internal Medicine 2, Oita University Faculty of Medicine, Japan
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Sonoda Hisako
Internal Medicine 2, Oita University Faculty of Medicine, Japan
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Komiya Kosaku
Internal Medicine 2, Oita University Faculty of Medicine, Japan
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Oka Hiroaki
Internal Medicine 2, Oita University Faculty of Medicine, Japan
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