ナノマテリアルの動態特性と免疫毒性

スポンサーリンク

概要

• 論文の詳細を見る

•   A diverse array of nanomaterials such as nanosilicas and carbon nanotubes are in widespread use due to the development of nanotechnology. Nanomaterials are already being applied in universal fields such as electronics, sunscreens, cosmetics, and medicine, because they have unique physicochemical properties such as high conductivity, strength, durability, and chemical reactivity. The advent of nanomaterials has also provided extraordinary opportunities for biomedical applications. However, the increasing use of nanomaterials has raised public concern about their potential risks to human health. In particular, recent reports have indicated that carbon nanotubes induced exaggerated inflammation and mesothelioma-like lesions in mice. However, few studies have examined the immunotoxicity of nanomaterials and it is essential to progress studies on the immunotoxicity of nanomaterials to ensure their safety. In this regard, we have attempted to elucidate the pharmacodynamics and immunotoxicity of nanomaterials, in order to develop novel safe nanomaterials and to establish scientifically based regulations. In this review, we would like to introduce our data on the immunotoxicity of nanosilicas, especially the relationship between physical properties (primary grain size, configuration and surface charge), pharmacodynamics of these materials, and their immunotoxicity. We consider that our study will improve the quality of human life by safely using nanomaterials, which can benefit society in general.

著者

• 吉岡 靖雄

  大阪大学臨床医工学融合研究教育センター

関連論文

• ナノマテリアルの動態特性と免疫毒性
• ナノマテリアルの安全確保に向けたNanoTox研究の最前線
• ナノマテリアルの安全確保に向けたNano-Safety Science研究
• ナノマテリアルの安全確保に向けた Nano-Safety Science 研究
• The Safety Assessment of Nanomaterials in Reproductive Developmental Field

スポンサーリンク