Changes in Activities of Enzymes Related to Malate-Aspartate Shuttle in Leukocytes from Dogs Given a Herb Supplement.
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概要
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Changes in activities of enzymes related to the malate-aspartate shuttle were measured in leukocytes (WBC) from dogs given food supplemented with 2 mg/kg of herb powder, Echevaria glauca, every day for 4 weeks. There were no significant differences in plasma concentrations of glucose, immunoreactive insulin, free fatty acids and triglyceride between dogs given food with or without the herb supplementation. Activities of malate dehydrogenase (MDH) and aspartate aminotransferase (AST) in the malate-aspartate shuttle increased remarkably in mitochondria of WBC from dogs fed the herb supplementation. It is suggested that Echevaria glauca herb supplementation might activate NADH shuttle systems and mitochondrial energy metabolism in dogs.
- 公益社団法人 日本獣医学会の論文
著者
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ARAI Toshiro
Division of Veterinary Biochemistry
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TAKAHASHI Mihoko
Division of Veterinary Biochemistry, Nippon Veterinary and Animal Science University
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SAKO Toshinori
Division of Internal Medicine, Nippon Veterinary and Animal Science University
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KAMATA Sachiko
Division of Internal Medicine, Nippon Veterinary and Animal Science University
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- Changes in Activities of Enzymes Related to Malate-Aspartate Shuttle in Leukocytes from Dogs Given a Herb Supplement.