Molecular Cloning and Phylogenetic Analysis of Inflammatory Cytokines of the Ferret (Mustela putorius furo)
スポンサーリンク
概要
- 論文の詳細を見る
The present study determined the cDNA and deduced amino acid sequences of ferret (Mustela putorius furo) inflammatory cytokines, interferon (IFN)-γ, interleukin (IL)-1β, IL-6, IL-8 and tumor necrosis factor (TNF)-α. The homologies of the nucleotide sequences of IFN-γ, IL-1β, IL-6, IL-8 and TNF-α of the ferret to those from other mammalian species ranged from 64.3-92.9%, 73.0-83.9, 58.1-84.8%, 58.1-89.7% and 79.0-95.0%, respectively. As distinctive amino acid residues constituting various motifs and ligand-binding sites and cysteine residues were highly conserved in ferret inflammatory cytokine proteins, ferret cytokines may have fundamentally similar functions to those of other mammals. Phylogenetic analyses based on the deduced amino acid sequences revealed that all ferret inflammatory cytokines were more closely related to those of the Carnivora order, specifically dog and cat, than to other species.
- 公益社団法人 日本獣医学会の論文
著者
-
Itou Takuya
Nihon Univ. Veterinary Res. Center Kanagawa
-
Sakai Takeo
Nihon Univ. Res. Center Kanagawa
-
NAKATA Makoto
Nihon University Veterinary Research Center
関連論文
- ブラジルの食肉目から分離された野外狂犬病ウイルスの系統学的解析(ウイルス学)
- Ocular Granulomatous Meningoencephalomyelitis in a Dog : Magnetic Resonance Images and Clinical Findings(Internal Medicine)
- Determination and Molecular Analysis of the Complete Genome Sequence of Two Wild-Type Rabies Viruses Isolated from a Haematophagous Bat and a Frugivorous Bat in Brazil
- ウイルス学:ブラジル野外狂犬病ウイルスのPおよびM遺伝子の特徴
- MRI of Secondary Cervical Syringomyelia in Four Cats
- バンドウイルカIFN-γcDNAのクローニングおよびシークエンス
- Three-dimensional analysis of the manipulation system in the lesser panda
- The morphological basis of the armor-like folded skin of the greater Indian rhinoceros as a thermoregulator
- Functional morphology of the forelimb muscles in an aardvark
- Absence of the guttural pouch in a newborn Indian rhinoceros demonstrated by three-dimensional image observations
- Three-dimensional reconstruction of the xenarthrous process of the thoracic and lumber vertebrae in the giant anteater
- Macroscopic observation and CT examination of the heart ventricular walls in the Asian elephant
- THREE-DIMENSIONAL CT ANALYSIS AND MACROSCOPIC OBSERVATIONS IN THE FORELIMB OF THE AARDVARK(Taxonomy and Systematics,Abstracts of papers presented at the 75^ Annual Meeting of the Zoological Society of Japan)
- Magnetic Resonance Imaging and Computed Tomography Findings of Vertebral Osteosarcoma in a Cat
- Astrocytoma in an African Hedgehog (Atelerix albiventris) Suspected Wobbly Hedgehog Syndrome
- Cloning and Quantification of Ferret Serum Amyloid A
- Geographical Distribution of Vampire Bat-related Cattle Rabies in Brazil
- Molecular Cloning and Phylogenetic Analysis of Inflammatory Cytokines of the Ferret (Mustela putorius furo)