Tubulopapillary Carcinoma with Spindle Cell Metaplasia of the Mammary Gland in a Cat

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概要

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• Sarcomatous proliferation of spindle cells was present in the mammary gland and many metastatic sites in a 10-year-old female domestic cat with tubulopapillary carcinoma in the mammary gland. Transition from neoplastic tubular structures to spindle cells in the primary site and fascicular proliferation of the spindle cells with or without coexistance of tubulopapillary carcinoma in the primary and metastatic sites were observed. Most of spindle cells were positive for cytokeratin CAM5.2 as well as the normal luminal epithelium but not the myoepithelium. From these results, this case was diagnosed as tubulopapillary carcinoma with spindle cell metaplasia and it was clarified that neoplastic luminal epithelial cells can transform to sarcomatous appearence.

• 公益社団法人 日本獣医学会の論文

著者

• KADOSAWA Tsuyoshi

  Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University

関連論文

• Predicting Metastatic Potential of Gastrointestinal Stromal Tumors in Dog by Ultrasonography
• Tubulopapillary Carcinoma with Spindle Cell Metaplasia of the Mammary Gland in a Cat
• Epidermal Growth Factor Receptor Expression in Canine Transitional Cell Carcinoma

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