18F-FDG and 11C-MET Positron Emission Tomography Findings of Cutaneous Mast Cell Tumor in a Dog
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概要
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A 12-year-old intact male Maltese dog presented with an inguinal mass. Histopathology revealed a grade III mast cell tumor. Computed tomography demonstrated pulmonary and inguinal nodules and masses. Chemotherapy was performed using a vinblastine/prednisone protocol, and the inguinal mass disappeared 5 weeks later. Use of 2-deoxy-2-[18F]fluoro-D-glucose (18F-FDG), and L-[methyl-11C]methionine (11C-MET)-positron emission tomography (PET) demonstrated hypermetabolic areas in the lungs and inguinal region one week after initial chemotherapy. The standardized uptake values of 18F-FDG were not different between lung and inguinal lesions; however, the inguinal lesion had a higher 11C-MET standardized uptake value than the lung lesions. The hypermetabolic area was still visible on the second 18F-FDG-PET scan despite the disappearance of the mass. This is the first report of 11C-MET-PET findings associated with a cutaneous mast cell tumor in a dog.
著者
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KIM Dae-Young
Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri
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Kang Min-Hee
BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Diseases and Department of Veterina
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Lim Chae-Young
BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Diseases and Department of Veterina
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PARK Hee-Myung
BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Diseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University
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KANG Byeong-Teck
Cerebral Microcirculation Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health
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PARK Hee-Myung
BK21 Program of Basic and Diagnostic Veterinary Specialist Program for Animal Diseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University
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PARK Hee-Myung
BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Disease and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University
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KANG Min-Hee
BK21 Program of Basic and Diagnostic Veterinary Specialist Program for Animal Diseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University
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LIM Chae-Young
BK21 Program of Basic and Diagnostic Veterinary Specialist Program for Animal Diseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University
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