Morphological Observation of Canine Natural Killer Cells Mediated Cytotoxicity.

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概要

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• The cytotoxic effects of canine NK cells on CL-1 target cells were examined by scanning electron microscopy (SEM). NK cell mediated cytotoxicity on CL-1 target cells was detected by 51Cr release assay. SEM showed that a canine NK cell extended projections to the CL-1 target cell. Furthermore, the surface of CL-1 target cells changed a mesh-like structure. Therefore, the cytotoxic effects of canine NK cells on CL-1 target cells were morphologically demonstrated.

• 公益社団法人 日本獣医学会の論文

著者

• KIUCHI Yoshihiro

  Laboratory Animal Facility, School of Medicine, Yokohama City University

• Nariai Koichi

  Laboratory Animal Facilities Research Center For Medical Sciences Jikei University School Of Medicin

• KUWABARA Masato

  College of Bioresource Sciences, Nihon University

• KUWABARA Masato

  College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0813, Japan

• KOSAKA Toshifumi

  College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0813, Japan

• NARIAI Koichi

  Laboratory Animal Facilities, Research Center for Medical Sciences, The Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo 105-0003, Japan

• NARIAI (NAKADA

  Laboratory Animal Facility, School of Medicine, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa 236-0004, Japan

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• Morphological Observation of Canine Natural Killer Cells Mediated Cytotoxicity.

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