Aborted Cardiac Arrest in a Patient Carrying KCNE1 D85N Variant during the Postpartum Period
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概要
- 論文の詳細を見る
The postpartum period is associated with an increased risk of fatal ventricular tachyarrhythmias in patients with congenital long QT syndrome (LQTS). We describe a 20-year-old female with LQTS who experienced aborted cardiac arrest during the postpartum period. Genetic screening identified a KCNE1 D85N variant, which has been reported to be a LQTS-causing gene variant, in the patient and her younger sister, whose QT interval was also prolonged. Since the allele frequency of this variant is almost 1%, it may be important to clarify whether such variant carriers indeed have an increased risk of fatal ventricular tachyarrhythmias during the postpartum period.
著者
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Nakajima Tadashi
Department of Medicine and Biological Science, Gunma University Graduate School of Medicine
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Kaneko Yoshiaki
Department of Medicine and Biological Science, Gunma University Graduate School of Medicine
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Manita Mamoru
Division of Cardiology, National Hospital Organization Takasaki National Hospital
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Iso Tatsuya
Department of Medicine and Biological Science, Gunma University Graduate School of Medicine
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Kurabayashi Masahiko
Department of Medicine and Biological Science, Gunma University Graduate School of Medicine
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Kaneko Yoshiaki
Department Of Cardiology The Heart Institute Of Japan Tokyo Women's Medical College
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Iso Tatsuya
Department Of Medicine And Biological Science
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Kurabayashi Masahiko
Department Of Cardiology Kanazawa Medical University
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Nakajima Tadashi
Department Of Applied Biology Faculty Of Textile Science And Technology Shinshu University
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