A Case of Syphilis Presenting with Initial Syphilitic Hepatitis and Serological Recurrence with Cerebrospinal Abnormality
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概要
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We present the case of an immunocompetent 50-year-old Japanese man with a cerebrospinal fluid (CSF) abnormality relevant to syphilis; his original presentation was liver dysfunction, the etiology of which was uncertain until positive serology for syphilis was identified. Liver dysfunction was promptly resolved after oral penicillin therapy; however, serological recurrence developed. CSF abnormality associated with syphilis was confirmed by subsequent lumbar puncture. Syphilis should be included in the differential diagnosis of patients with liver dysfunction of unknown etiology, and possible neurosyphilis should be considered when the treatment becomes refractory, even when there is no evidence of neurological manifestations.
著者
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Miura Hideaki
Department of Internal Medicine, Social Insurance Central General Hospital
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Nakano Masayuki
Department of Pathology, Ofuna Chuo Hospital
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Ryu Tomiko
Department of Internal Medicine, Social Insurance Central General Hospital
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Kitamura Shigehiro
Department of Pathology, Social Insurance Central General Hospital
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Suzaki Ai
Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medic
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Miura Hideaki
Department Of Bio And Applied Chemistry Graduate School Of Engineering Toyo University
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Kitamura Shigehiro
Department Of Pathology Social Insurance Chuo General Hospital
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Nakano Masayuki
Department Of Electrical Engineering Hiroshima University
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Suzaki Ai
Division of General Medicine, Department of Internal Medicine, Nihon University School of Medicine, Japan
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Suzaki Ai
Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine
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