Automated Assessment of Myocardial Viability After Acute Myocardial Infarction by Global Longitudinal Peak Strain on Low-Dose Dobutamine Stress Echocardiography
スポンサーリンク
概要
- 論文の詳細を見る
Background: Low-dose dobutamine stress echocardiography (DSE) assesses myocardial viability at the early stage of acute myocardial infarction (AMI), but its assessment is subjective and variable. Automated function image (AFI) determines global longitudinal peak strain (GLPS) based on tissue tracking technique. The ability of GLPS obtained by AFI during dobutamine stress to assess myocardial viability after AMI was investigated. Methods and Results: Low-dose DSE at day 3 in 23 consecutive patients with AMI was performed using Vivid 7 (GE Healthcare). Segmental longitudinal peak strain with AFI and obtained GLPS was analyzed. Wall motion score index (WMSI) by echocardiography 1 month later was determined. In 18 patients, left ventriculography was also performed at 3.2±1.5 months later to obtain left ventricular ejection fraction (LVEF) and regional wall motion (RWM, SD/chord). GLPS was improved during dobutamine infusion at 10 μg · kg-1 · min-1 (-12.9±3.5% to -15.2±3.6%, P=0.0004). GLPS during dobutamine stress showed good correlations with follow-up WMSI (R=0.47, P=0.02), with peak CK-MB (R = 0.52, P=0.01), with RWM (R = -0.48, P=0.04), and with LVEF (R = -0.54, P=0.02), whereas GLPS at baseline showed no correlations with them. Averaged segmental peak strain at baseline and during stress were correlated with follow-up WMSI (R = 0.50 and 0.43, respectively), but not with LVEF. Conclusions: GLPS during dobutamine stress determined by AFI is a promising, objective index to assess myocardial viability on the early stage of AMI.
著者
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Iwakura Katsuomi
Division of Cardiology, Sakurabashi Watanabe Hospital
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Koyama Yasushi
Division of Cardiology, Sakurabashi Watanabe Hospital
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Date Motoo
Division of Cardiology, Sakurabashi Watanabe Hospital
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Higuchi Yoshiharu
Division of Cardiology, Sakurabashi Watanabe Hospital
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Inoue Koichi
Division of Cardiology, Sakurabashi Watanabe Hospital
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Kimura Ryusuke
Division of Cardiology, Sakurabashi Watanabe Hospital
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Nagai Hiroyuki
Division of Cardiology, Sakurabashi Watanabe Hospital
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Toyoshima Yuko
Division of Cardiology, Sakurabashi Watanabe Hospital
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Imai Michio
Division of Cardiology, Sakurabashi Watanabe Hospital
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Ozawa Makito
Division of Cardiology, Sakurabashi Watanabe Hospital
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Okazaki Yukinori
Division of Cardiology, Sakurabashi Watanabe Hospital
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Shibuya Masahiko
Division of Cardiology, Sakurabashi Watanabe Hospital
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Fujii Kenshi
Division of Cardiology, Sakurabashi Watanabe Hospital
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Okamura Atsushi
Division of Cardiology, Sakurabashi Watanabe Hospital
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Ito Norihisa
Division of Cardiology, Sakurabashi Watanabe Hospital
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Omiya Shigemiki
Division of Cardiology, Sakurabashi Watanabe Hospital
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Takagi Takashi
Division of Cardiology, Sakurabashi Watanabe Hospital
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Morisawa Daisuke
Division of Cardiology, Sakurabashi Watanabe Hospital
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