Alcohol Consumption and Digestive Cancer Mortality in Koreans: The Kangwha Cohort Study

スポンサーリンク

概要

• 論文の詳細を見る

• Background: Alcohol consumption is a known risk factor for cancers of the mouth, esophagus, liver, colon, and breast. In this study, we examined the association between alcohol consumption and digestive cancer mortality in Korean men and women.Methods: A cohort of 6291 residents of Kangwha County who were aged 55 years or older in March 1985 were followed to 31 December 2005—a period of 20.8 years. We calculated the relative risks of cancer mortality with respect to the amount of alcohol consumed. Cox proportional hazard model was used to adjust for age at entry, smoking, ginseng intake, education status, and pesticide use.Results: In men, the risks of mortality from esophageal cancer (relative risk [RR], 5.62; 95% confidence interval [CI], 1.45–21.77) and colon cancer (RR, 4.59; 95% CI, 1.10–19.2) were higher among heavy drinkers, as compared with abstainers. The risks of mortality from colon cancer and bile duct cancer rose with increasing alcohol consumption; these trends were positive and statistically significant (P = 0.04 and P = 0.02, respectively). When participants were stratified by type of alcoholic beverage, soju drinkers had higher risks of mortality from esophageal cancer and colon cancer than makkoli drinkers. In women, the risk of digestive cancer mortality was higher among alcohol drinkers than abstainers, but this difference was not statistically significant.Conclusions: Alcohol consumption increases mortality from esophageal cancer and colon cancer in men.

著者

• NAM Chung

  Department of Preventive Medicine, Yonsei University College of Medicine

• Yi Sang-Wook

  Department of Preventive Medicine and Public Health, Kwandong University College of Medicine

• Sull Jae

  Institute for Health Promotion, Graduate School of Public Health, Yonsei University

• Linton John

  Department of Family Medicine, Yonsei University College of Medicine

• Ohrr Heechoul

  Institute for Health Promotion, Graduate School of Public Health, Yonsei University

関連論文

• Algae Consumption and Risk of Type 2 Diabetes : Korean National Health and Nutrition Examination Survey in 2005
• Alcohol Consumption and Digestive Cancer Mortality in Koreans: The Kangwha Cohort Study
• Progression Rate From New-Onset Pre-Hypertension to Hypertension in Korean Adults
• Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population
• High-Density Lipoprotein-Cholesterol and Ischemic Heart Disease Risk in Korean Men With Cardiac Risk : A Prospective Cohort Study
• A novel 111/121 diplotype in the Calpain-10 gene is associated with type 2 diabetes
• Cost-effective mammography screening in Korea : High incidence of breast cancer in young women
• Alcohol Consumption and Digestive Cancer Mortality in Koreans : The Kangwha Cohort Study

スポンサーリンク