Alcohol Consumption and Digestive Cancer Mortality in Koreans : The Kangwha Cohort Study
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概要
- 論文の詳細を見る
Background: Alcohol consumption is a known risk factor for cancers of the mouth, esophagus, liver, colon, and breast. In this study, we examined the association between alcohol consumption and digestive cancer mortality in Korean men and women.Methods: A cohort of 6291 residents of Kangwha County who were aged 55 years or older in March 1985 were followed to 31 December 2005—a period of 20.8 years. We calculated the relative risks of cancer mortality with respect to the amount of alcohol consumed. Cox proportional hazard model was used to adjust for age at entry, smoking, ginseng intake, education status, and pesticide use.Results: In men, the risks of mortality from esophageal cancer (relative risk [RR], 5.62; 95% confidence interval [CI], 1.45–21.77) and colon cancer (RR, 4.59; 95% CI, 1.10–19.2) were higher among heavy drinkers, as compared with abstainers. The risks of mortality from colon cancer and bile duct cancer rose with increasing alcohol consumption; these trends were positive and statistically significant (P = 0.04 and P = 0.02, respectively). When participants were stratified by type of alcoholic beverage, soju drinkers had higher risks of mortality from esophageal cancer and colon cancer than makkoli drinkers. In women, the risk of digestive cancer mortality was higher among alcohol drinkers than abstainers, but this difference was not statistically significant.Conclusions: Alcohol consumption increases mortality from esophageal cancer and colon cancer in men.
- 日本疫学会の論文
- 2010-05-01
著者
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Yi Sang-Wook
Department of Preventive Medicine and Public Health, Kwandong University College of Medicine
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Ohrr Heechoul
Institute for Health Promotion, Graduate School of Public Health, Yonsei University
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Woong Sull
Institute For Health Promotion & Department Of Epidemiology And Health Promotion Graduate School
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Yi Sang-wook
Department Of Preventive Medicine And Public Health Kwandong University College Of Medicine
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Ohrr Heechoul
Institute For Health Promotion Graduate School Of Public Health Yonsei University
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Woong Sull
Institute For Health Promotion Graduate School Of Public Health Yonsei University
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Mo Nam
Department Of Preventive Medicine And Public Health Yonsei University College Of Medicine
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ALDERMAN LINTON
Department of Family Medicine, Yonsei University College of Medicine
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Alderman Linton
Department Of Family Medicine Yonsei University College Of Medicine
関連論文
- Alcohol Consumption and Digestive Cancer Mortality in Koreans: The Kangwha Cohort Study
- Serum Adiponectin Is Associated with Smoking Status in Healthy Korean Men
- Alcohol Consumption and Digestive Cancer Mortality in Koreans : The Kangwha Cohort Study