Acute Kidney Injury Caused by Zonisamide-Induced Hypersensitivity Syndrome
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概要
- 論文の詳細を見る
Drug rash with eosinophilia and systemic symptoms (DRESS), also known as drug-induced hypersensitivity syndrome (DIHS), is a severe adverse drug reaction affecting multiple organs caused by drug treatment. The current report describes a man who was prescribed zonisamide for epilepsy and subsequently developed widespread skin rash, acute kidney injury, high-grade fever, eosinophilia, liver dysfunction, lymphadenopathy and an increase in antihuman herpesvirus-6 immunoglobulin G titer. Hypersensitivity to zonisamide was confirmed by the skin patch test. Based on these findings, the patient was diagnosed with DRESS/DIHS caused by zonisamide. This is the first report of acute kidney injury due to zonisamide-induced DRESS/DIHS.
著者
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HASEGAWA Midori
Department of Nephrology, Fujita Health University School of Medicine
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MATSUNAGA Kayoko
Department of Dermatology, Fujita Health University School of Medicine
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Nakai Shigeru
Division Of Clinical Engineering Technology Fujita Health University College
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Murakami Kazutaka
Department Of Nephrology School Of Medicine Fujita Health University
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Matsunaga Kayoko
Department Of Dermatology Fujita Health University
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FUJITA Yoshiro
Department of Nephrology and Rheumatology, Toyota Memorial Hospital
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Tomita Makoto
Department Of Mathematical Sciences Nanzan University
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Nabeshima Kuihiro
Department of Nephrology, Fujita Health University School of Medicine
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Yamakita Takashi
Department of Dermatology, Fujita Health University School of Medicine
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