Cellular Lipid Droplets and Hepatitis C Virus Life Cycle

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概要

• 論文の詳細を見る

• Lipid droplets (LDs) are cellular lipid storage organelles involved not only in lipid homeostasis but also in a variety of diseases. Chronic hepatitis C virus (HCV) infection affects host lipid metabolism, and thus induces LD accumulation in the liver. Recent studies have suggested that cellular LDs also play a crucial role in the HCV life cycle. Interactions between HCV proteins, especially the core protein, and LDs are required for the morphogenesis of infectious HCV. The present minireview will summarize the recent research progress about this unique relationship between LDs and the HCV life cycle.

著者

• Fukasawa Masayoshi

  Department Of Biochemistry And Cell Biology National Institute Of Infectious Diseases

関連論文

• Expression of Cholesteryl Ester Transfer Protein in Human Atherosclerotic Lesions and Its Implication in Reverse Cholesterol Transport
• Proteomic Profiling of Lipid Droplet Proteins in Hepatoma Cell Lines Expressing Hepatitis C Virus Core Protein
• Cellular Lipid Droplets and Hepatitis C Virus Life Cycle
• Enhancement of de Novo Fatty Acid Biosynthesis in Hepatic Cell Line Huh7 Expressing Hepatitis C Virus Core Protein(Biochemistry)

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