Subacute Effects of Capsaicinoids on the Distribution of White Blood Cells in Rats
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概要
- 論文の詳細を見る
The subacute effects of dihydrocapsaincin (DHC) and capsaicin (CAP) (dose=3 mg/kg body weight per day for 10 days, subcutaueous) on the number and distribution of white blood cells (WBCs) were studied in male adult rats. The administration of DHC and CAP for 10 days decreased significantly the number of total WBCs, lymphocytes and monocyte, and increased significantly the number of the neutrophil and eosinophil without changing the number of basophil. The administration of DHC significantly decreased thymus weight and increased adrenal weight, showing that DHC induced thymus atrophy and adrenal hypertrophy. These results suggest that capsaicinoids induced the decrease of acquired immunity responses and these phenomena may have in part participated in capsaicinoids-induced stress-responses in rats.
- 公益社団法人 日本薬学会の論文
著者
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IMAIZUMI Kazuhiko
Laboratory of Physiological Sciences, Faculty of Human Sciences, Waseda University
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SATO Shogo
Laboratory of Physiological Sciences, Faculty of Human Sciences, Waseda University
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BAN Takamasa
Laboratory of Physiological Sciences, Faculty of Human Sciences, Waseda University
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TACHIYASHIKI Kaoru
Department of Living and Health Sciences, Joetsu University of Education
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TANIHATA Jun
Laboratory of Physiological Sciences, Faculty of Human Sciences, Waseda University
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Ban Takamasa
Laboratory Of Physiological Sciences Faculty Of Human Sciences Waseda University
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Imaizumi Kazuhiko
Laboratory Of Physiological Sciences Faculty Of Human Sciences Waseda University
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Aritoshi Shoko
Lab. Of Physiological Sciences Fac. Of Human Sciences Waseda Univ.
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Aritoshi Shoko
Laboratory Of Physiological Sciences Faculty Of Human Sciences Waseda University
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Sato Shogo
Laboratory Of Physiological Sciences Faculty Of Human Sciences Waseda University
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KUMAZAWA Mari
Laboratory of Physiological Sciences, Faculty of Human Sciences, Waseda University
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Tachiyashiki Kaoru
Department Of Living And Health Sciences Graduate School Of Education Joetsu University Of Education
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Kumazawa Mari
Laboratory Of Physiological Sciences Faculty Of Human Sciences Waseda University
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Tachiyashiki Kaoru
Department of Natural and Health Sciences, Joetsu University of Education
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