Isolated Granulomatous Renal Arteritis: A Variant Form of Giant Cell Arteritis with Few Macrophages
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概要
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A 64-year-old woman with hypertension and hyperlipidemia was admitted to our hospital for the investigation and management of general fatigue, anorexia, a 5-kg weight loss, and a 4-week history of high-grade fever. She had no symptoms of headache, myalgia, or arthralgia, and the physical examination was unremarkable. The laboratory tests revealed renal dysfunction with urine abnormalities that had not been observed 1 year earlier. A renal biopsy showed granulomatous small arteritis without necrotic lesions or glomerular pathology. An immunohistochemical study of the infiltrating leukocytes showed a predominance of CD4+ T cells followed by CD8+ T cells, and only a few macrophages. The condition drastically improved after treatment with 30 mg/day of oral prednisolone. The granulomatous renal arteritis was considered a variant of giant cell arteritis, because it showed the peculiar finding of a few macrophages in the granulomatous lesions.
- 社団法人 日本内科学会の論文
著者
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Nakaya Izaya
Department of Internal Medicine, Toyama Prefectural Central Hospital
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SAKUMA Tsutomu
Department of Thoracic Surgery, Kanazawa Medical University
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Watanabe Ryu
Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine
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Nakaya Izaya
岩手県立中央病院 腎臓内科
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Nakaya Izaya
Department Of Gastroenterology And Nephrology Kanazawa University Graduate School Of Medicine
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Kudo Hiroki
Department of Nephrology, Iwate Prefectural Central Hospital
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Yahata Mayumi
Department of Nephrology, Iwate Prefectural Central Hospital
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Soma Jun
Department of Nephrology, Iwate Prefectural Central Hospital
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Sakuma Tsutomu
Department Of Bioscience And Chemistry Faculty Of Agriculture Hokkaido Unversity
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Soma Jun
Department Of Nephrology Iwate Prefectural Central Hospital
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Yahata Mayumi
Department Of Nephrology Iwate Prefectural Central Hospital
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