Vibralactones D-F from Cultures of the Basidiomycete Boreostereum vibrans
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概要
- 論文の詳細を見る
Three new metabolites, vibralactones D—F (1—3) were isolated from cultures of the basidiomycete Boreostereum vibrans. The relative configuration of 1 was established on the basis of X-ray diffraction analysis, while the absolute configurations of 1—3 were assigned using a modified Mosher's method. Compound 1 showed weak inhibitory activities against isozymes of 11β-hydroxysteroid dehydrogenases (HSD) with IC50 values of 85.7 μM (human HSD1), 295.2 μM (mouse HSD1), and 87.1 μM (human HSD2).
- 公益社団法人 日本薬学会の論文
著者
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Liu Ji-kai
State Key Lab. Of Phytochemistry And Plant Resource In West China Kunming Inst. Of Botany Chinese Ac
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Jiang Meng-Yuan
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botan
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Dong Ze-jun
State Key Lab. Of Phytochemistry And Plant Resources In West China Kunming Inst. Of Botany Chinese A
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Leng Ying
Shanghai Institute Of Materia Medica Chinese Academy Of Sciences
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Zhang Ling
State Key Lab. Of Phytochemistry And Plant Resources In West China Kunming Inst. Of Botany Chinese A
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Jiang Meng-Yuan
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences
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Yang Zhu-Liang
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences
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