Advanced Gastric Cancer Patient with Peritonitis Carcinomatosa Successfully Treated with a Combination Therapy of Paclitaxel and TS-1, but Relapsed with Multiple Bone Metastasis and Died from Rapidly Progressive Meningitis Carcinomatosa —Advanced Gastric
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概要
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A 59-year-old man diagnosed as gastric cancer with peritonitis carcinomatosa was treated with paclitaxel and TS-1; 60 mg/m2/day of paclitaxel was given on days 1 and 8, and 60-80 mg/m2/day of TS-1 was given for 2 weeks. Six courses of combination therapy were administered, and the ascites disappeared completely. Because multiple bone metastases occurred, we attempted combination therapy with cisplatin and irinotecan hydrochloride; 50 or 30 mg/m2/day of cisplatin was given on day 1 or day 15, and 70 mg/m2/day of irinotecam hydrochloride was given on days 1 and 15. The patient achieved a remarkable response, however, intrameningeal dissemination occurred and he died from rapidly progressive meningitis carcinomatosa.
著者
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Watanabe Takuya
Department Of Biochemistry Showa University School Of Medicine
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Yoneoka Yuichiro
Department Of Neurosurgery Brain Research Institute Niigata University
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Soga Kenji
Department Of Internal Medicine And Gastroenterology Medical Hospital The Nippon Dental University S
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Hirono Haruka
Department Of Internal Medicine And Gastroenterology Medical Hospital The Nippon Dental University S
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Hasegawa Katsuhiko
Department Of Internal Medicine And Gastroenterology Medical Hospital The Nippon Dental University S
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Shibasaki Koichi
Department Of Internal Medicine And Gastroenterology Medical Hospital The Nippon Dental University S
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Yoneoka Yuichiro
Department of Neurosurgery, Graduate School of Medical and Dental Sciences, University of Niigata
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