Relapsing Campylobacter Coli Bacteremia with Reactive Arthritis in a Patient with X-linked Agammaglobulinemia
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概要
- 論文の詳細を見る
A patient genetically diagnosed with X-linked agammaglobulinemia repeatedly developed bacteremia due to Campylobacter coli (C. coli) for one year and seven months in spite of immunoglobulin replacement therapy. Throughout the clinical course, C. coli with identical genetic patterns was repeatedly isolated from both blood and stool cultures, thus indicating that the patient had latent intestinal infection. The bacteremia was always accompanied by reactive arthritis. Since the immunoglobulin level was extremely low with severe B cell deficiency, the reactive arthritis must have been induced in a humoral immunity-independent manner. Adding oral minocycline following intravenous meropenem was very effective; the stool cultures became negative and the patient has been well for more than one year without relapse of bacteremia.
- 社団法人 日本内科学会の論文
著者
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Arai Ayako
Department Of Hematology Tokyo Medical And Dental University
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Sawabe Etsuko
Department Of Clinical Laboratory Tokyo Medical And Dental University Hospital
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Kanegane Hirokazu
Department Of Pediatrics Faculty Of Medicine Toyama Medical And Pharmaceutical University
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Miyawaki Toshio
Department Of Department Of Pediatrics Graduate School Of Medicine University Of Toyama
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Miura Osamu
Department Of Ecology And Evolutionary Biology Graduate School Of Life Sciences University Of Tohoku
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Kanegane Hirokazu
Department of Pediatrics, Faculty of Medicine, Toyama University
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Miyawaki Toshio
Department of Pediatrics, Faculty of Medicine, Toyama University
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Kitano Asako
Department of Hematology, Tokyo Madical and Dental University
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Arai Ayako
Department of Hematology, Tokyo Madical and Dental University
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