Intoxication with Over-the-Counter Antitussive Medication Containing Dihydrocodeine and Chlorpheniramine Causes Generalized Convulsion and Mixed Acidosis
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概要
- 論文の詳細を見る
We report a 35-year-old man who was referred to our hospital with generalized convulsion and mixed acidosis presumably caused by abuse of SS-BRONTM tablets, an over-the-counter (OTC) antitussive medication sold in Japan. These tablets contain dihydrocodeine phosphate, methylephedrine, chlorpheniramine, and caffeine. Although it is difficult to discern which component caused these symptoms, it seems that dihydrocodeine phosphate or methylephedrine was involved in the addiction to SS-BRONTM and chlorpheniramine may have caused the generalized convulsion. It should be recognized that an OTC antitussive, which is quite easy to obtain, can be abused and subsequently induce serious intoxication.
- 社団法人 日本内科学会の論文
著者
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Sekikawa Takashi
Department Of Internal Medicine Toyosu Hospital Showa University
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Murao Satoshi
Department Of Bone And Joint Surgery Seirei Hamamatsu General Hospital
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Yamashita Tetsuji
Department Of Chemistry Faculty Of Engineering Gifu University
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Sekikawa Takashi
Department of Internal Medicine, Matsuyama Shimin Hospital
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Manabe Hiroaki
Department of Neurosurgery, Matsuyama Shimin Hospital
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Yamashita Tetsuji
Department of Internal Medicine, Matsuyama Shimin Hospital
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- Intoxication with Over-the-Counter Antitussive Medication Containing Dihydrocodeine and Chlorpheniramine Causes Generalized Convulsion and Mixed Acidosis
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