New-onset Diabetic Ketoacidosis Induced by the Addition of Perospirone Hydrochloride in a Patient Treated with Risperidone
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概要
- 論文の詳細を見る
A 32-year-old man with a family history of type 2 diabetes mellitus presented with circulatory collapse and deep coma after 9 days of treatment with perospirone hydrochloride, a recently developed atypical antipsychotic agent available only in Japan. The new drug had been added to the long-standing treatment with risperidone. Diagnosed with diabetic ketoacidosis, he was given insulin and saline with discontinuation of all antipsychotics. Ultimately, diabetes was controlled by dietary therapy alone despite reintroduction of risperidone. The risk of new-onset diabetic ketoacidosis in patients with diabetic risk factors who are taking perospirone hydrochloride or other atypical antipsychotics should be kept in mind.
- 社団法人 日本内科学会の論文
著者
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Hamanaka Satoko
Department Of Psychiatry Kitasato University School Of Medicine
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Kamijo Yoshito
Department of Emergency & Critical Care Medicine, School of Medicine, Kitasato University of Kanagawa, Japan
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Kamijo Yoshito
Department of Emergency and Critical Care Medicine, Kitasato University School of Medicine
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- Intermittent Complete Atrioventricular Block after Long Term Low-Dose Carbamazepine Therapy with a Serum Concentration Less than the Therapeutic Level
- New-onset Diabetic Ketoacidosis Induced by the Addition of Perospirone Hydrochloride in a Patient Treated with Risperidone