Prolactin Levels in Schizophrenic Patients Receiving Perospirone in Comparison to Risperidone
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概要
- 論文の詳細を見る
Serum prolactin levels were investigated in 41 patients with schizophrenia who were receiving clinically effective doses of perospirone or risperidone for more than 4 weeks. In order to determine baseline prolactin levels, blood samples were obtained in the morning, 10 – 14 h after antipsychotic medication. Median levels were within normal limits in both female and male patients receiving perospirone, while risperidone induced significant elevation. These results suggest that in contrast to risperidone, where baseline prolactin levels were elevated 5.3-fold in female and 4.2-fold in male patients, baseline prolactin levels are not elevated after treatment with perospirone. However, these results should be cautiously interpreted, because drug-by-time interaction has previously been reported in antipsychotic-induced hyperprolactinemia.
- 社団法人 日本薬理学会の論文
- 2003-03-01
著者
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KOSAKA Kenji
St. Marianna Medical Institute
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UCHIKADO Hirotake
Department of Psychiatry, Yokohama City University School of Medicine
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KOSAKA Kenji
Department of Psychiatry, Yokohama City University
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Togo Takashi
Department Of Psychiatry School Of Medicine Yokohama City University
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Kosaka Kenji
Fukushimura Hospital
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Kosaka Kenji
Department Of Psychiatry Yokohama City University School Of Medicine
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Uchikado Hirotake
Department Of Psychiatry Of Psychiatry Yokohama City University School Of Medicine
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Uchikado Hirotake
Department Of Neuroscience Mayo Clinic
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ISEKI Eizo
Department of Psychiatry, Yokohama City University
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Iseki E
Department Of Psychiatry Juntendo Tokyo Koto Geriatric Medical Center Juntendo University School Of
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Iseki Eizo
Department Of Psychiatry Juntendo Tokyo Koto Geriatric Medical Center Juntendo University School Of
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Shoji Mika
Yokohama Maioka Hospital
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KATSUSE Omi
Department of Psychiatry, Yokohama City University School of Medicine
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TOGO Takashi
Yokohama Maioka hospital
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OYAMA Ikuko
Yokohama Maioka hospital
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KASE Akihiko
Yokohama Maioka hospital
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Katsuse Omi
Department Of Neurosurgery Graduate School Of Medicine Tokyo Medical And Dental University
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Iseki Eizo
Department Of Psychiatry Juntendo Tokyo Koto Geriatric Medical Center Juntendo University School Of
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Katsuse Omi
Department Of Psychiatry Yokohama City University School Of Medicine
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Kosaka Kenji
Department Of Physical Therapy Saitama Medical School Junior College
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Kosaka Kenji
Department Of Geriatric Medicine Ehime University Graduate School Of Medicine
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Kasanuki Koji
Pet/ct Dementia Research Center Juntendo Tokyo Koto Geriatric Medical Center
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