MRI位相差法によるRadiofrequency ablationの温度モニタリング

概要

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Upon the development of a customized magnetic resonance imaging (MRI)-compatible probe for the interstitial deposition of radiofrequency (RF) energy, we monitored ex vivo RF ablation (RFA) with MRI a 1.5T. We proposed to visualize the dynamics of the RFA with temperature mapping based on the temperature dependence of the water proton resonance frequency shift. The MR-compatible probe produced minimal artifact and allowed visualization and mapping of the tissue adjacent to the probe. Phase mapping obtained by calculation of phase differences provided clear visualization of the generated temperature gradients. Multi-slice images provided a 3-D appreciation of the heated volume. Dynamic quantitative thermal mapping derived from MRI obtained during RFA will be essential for the optimization of RFA in clinical applications.
特定非営利活動法人 Microwave Surgery研究会の論文