Spontaneous Glioblastoma Multiforme in an AKR/J Sea Mouse
スポンサーリンク
概要
- 論文の詳細を見る
A spontaneous brain tumor was found in a 46-week-old male AKR/J Sea mouse. The tumor occupied the forebrain, and invaded the nasal mucosa of nose along the nerve. The tumor cells showed a wide variety of sizes and shapes; round, polygonal, oval, and fusiform with eosinophilic cytoplasm. Bizarre giant cells with multiple nuclei, foci of necrosis and hemorrhage, and mitotic figures were common findings. According to these findings, the tumor was diagnosed as glioblastoma multiforme, a highly malignant astrocytic neoplasm. The tumor cells reacted negatively against the antibody for glial fibrillary acidic protein (GFAP), and had no glial filaments under ultrastructural examination. It is presumed that those immunocytochemical and ultrastructural findings show poor differentiation in this case.
著者
-
TSUCHITANI Minoru
Mitsubishi Chemical Safety Institute Ltd.
-
Wako Yumi
Mitsubishi Chemical Safety Institute Ltd.
-
DOI Takuya
Mitsubishi Chemical Safety Institute Ltd.
-
OKAZAKI Yoshimasa
Mitsubishi Chemical Safety Institute Ltd.
-
KATSUTA Osamu
Mitsubishi Chemical Safety Institute Ltd.
-
Yokoyama Mitsue
Mitsubishi Chemical Safety Institute Ltd.
関連論文
- Malignant Mesothelioma in the Thoracic Cavity of a Crj:CD(SD) Rat Characterized by Round Hyalinous Stroma
- 22D-10-4 Induction of replicative DNA synthesis (RDS) in rat livers following sibgle inhalation exposure to carbon tetrachloride.
- Effects of DBP and DEHP on in vivo Estrogenic Activities in Ovariectomized Rats.
- 2B-12 Induction of replicative DNA synthesis (RDS) in liver and kidney of mice and rats following a single inhalation exposure with tetrachloroethylene
- Vascular Lesion in the Meninx and Retina Following Administration of 3,3'-Iminodipropionitrile (IDPN) in Rats
- EVALUATION OF A TWO-GENERATION REPRODUCTION TOXICITY STUDY ADDING ENDOPOINTS TO DETECT ENDOCRINE DISRUPTING ACTIVITY USING VINCLOZOLIN
- EVALUATION OF A TWO-GENERATION REPRODUCTION TOXICITY STUDY ADDING ENDOPOINTS TO DETECT ENDOCRINE DISRUPTING ACTIVITY USING LINDANE
- P7-29 Clinical pathological characteristics of a spontaneous dwarf mutation in BriHan : WIST@Jcl(GALAS) rat(IMMUNE AND ALLERGIC SYSTEM/KIDNEYS AND URINARY EXCRETION SYSTEM/CYTOTOXICITY/OTHERS-1)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 3
- Morphological and Endocrinological Characteristics of the Endocrine Systems in Wistar Hannover GALAS Rats Showing Spontaneous Dwarfs
- Morphological Characteristics of Bone in Dwarf Rats Derived from Wistar Hannover GALAS Rats
- P-50 Effect of Aniline on Motor Activity in Rats.(Proceedings of the 27th Annual Meeting)
- 22B-11-2 Neurotoxic Potentiality of Aniline derivatives (p-fluoroaniline, p-chloroaniline, p-iodoaniline, p-bromoaniline) in Rats.
- A Pseudotumorous Nodular Lesion of the Subcutis in a Beagle Dog Comparable to Calcifying Fibrous Pseudotumor in Human
- P-52 The Examination of Quantitative Analysis using Image Analyzer on the Expression of Glial Fibrillary Acidic Protein (GFAP) in the Brain of Rats Received Trimethyltin.(Proceedings of the 27th Annual Meeting)
- Motor Nerve Conduction Velocities during Growth of SD Rats Fed ad libitum or Restricted Diets
- Unusual Lipomatous Lesion with Extramedullary Hematopoiesis Possibly Derived from Ito (Perisinusoidal) Cells in a CD-1 Mouse
- Chronic cadmium treatment induces islet B cell injury in ovariectomized cynomolgus monkeys
- P10-16 Increased osteoid volume and iron deposition of the Iumbar vertebra in a chronic cadmium toxicosis model of cynomolgus monkeys.
- 21D-04-1 Quantitative Analysis of Bone Lesion in Ovariectomized Cynomolgus Monkeys Given Repeated Intravenous Injections of CdCl_2.
- Anatomical Structure and Surface Epithelial Distribution in the Nasal Cavity of the Common Cotton-Eared Marmoset (Callithrix jacchus)
- OCCURRENCE OF TOXICITY AND CELL PROLIFERATION AFTER A SINGLE GAVAGE ADMINISTRATION OF CHLOROFORM TO MALE F344 RATS
- Deposition Process of Eosinophilic Substance in Mouse Nasal Septum
- ACUTE TOXICITY OF CADMIUM IN RATS WITH OR WITHOUT CADMIUM PRETREATMENT
- 302 EFFECTS OF CADMIUM CHLORIDB ON THE BLOOD AND URINARY EXAMINATIONS IN OVARIECTOMIZED RATS
- Air Containing Ions Generated by Electric Discharge Has No Potential to Induce DNA Damage in Lung Cells in Rats and Mice
- Spontaneous Glioblastoma Multiforme in an AKR/J Sea Mouse
- Ganglion-Like Cells in Relation to C-cell Proliferation of the Thyroid Gland in Rats
- Mixed Thymoma in a Young Cynomolgus Monkey (Macaca fascicularis)
- Malignant Mesothelioma in the Thoracic Cavity of a Crj:CD(SD) Rat Characterized by Round Hyalinous Stroma
- Naturally Occurring Helicobacter pylori Infection in the Cynomolgus Monkey (Macaca fascicularis) Used in Subclinical Studies
- Neuropathological Evaluation of Acrylamide- and 3,3'-Iminodipropionitrile-Induced Neurotoxicity in a Rat 28-Day Oral Toxicity Study-Collaborative Project for Standardization of Test Procedures and Evaluation of Neurotoxicity
- The Progression and Recovery of Neurotoxicity Induced by A Single Oral Dose of Aniline in Rats
- A Case of Adenocarcinoma of the Endometrium Extending into the Leiomyoma of the Uterus in a Rabbit
- Gangliocytoma with Immature Neuronal Cell Elements in the Pituitary of a Rat.