Nonsynonymous Site Heteroplasmy in Fish Mitochondrial DNA
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概要
- 論文の詳細を見る
Heteroplasmic nucleotide polymorphisms are rarely observed in wild animal mitochondrial DNA. The occurrence of such site heteroplasmy is expected to be extremely rare at nonsynonymous sites where the number of nucleotide substitutions per site is low due to functional constraints. This report deals with nonsynonymous mitochondrial heteroplasmy from two wild fish species, chum salmon and Japanese flounder. We detected an A/C nonsynonymous heteroplasmic site corresponding to putative amino acids, Ile or Met, in NADH dehydrogenase subunit-5 (ND5) region of chum salmon. The heteroplasmic site was at the 3rd position of 58th codon. As for Japanese flounder we detected a C/T nonsynonymous heteroplasmic site corresponding to putative amino acids, Leu or Pro, in ND4 region. The heteroplasmic site was at the 2nd position of 450th codon. We also verified heteroplasmy at these sites by sequencing cloned fragments.
- 日本遺伝学会の論文
- 2005-08-25
著者
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Ida H
Kitasato Univ. Iwate Jpn
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Ida Hitoshi
Kitasato Univ. Iwate Jpn
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Shigenobu Yuya
Tohoku National Fisheries Research Institute
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SAITOH Kenji
Tohoku National Fisheries Research Institute
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Hayashizaki Ken-ichi
Department Of Marine Biosciences School Of Fisheries Sciences Kitasato University
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Hayashizaki K
School Of Fisheries Science Kitasato University
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Ida H
Prec Institute Inc.
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SHIGENOBU Yuya
Department of Fisheries Science, Kitasato University
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IDA Hitoshi
Department of Fisheries Science, Kitasato University
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Saitoh Kenji
Tohoku National Fisheries Res. Inst. Miyagi Jpn
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Ida Hitoshi
Department Of Fisheries Science Kitasato University
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Hayashizaki Ken-ichi
Department of Fisheries Science, Kitasato University
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