φ80追加感染阻害遺伝子(cor)のクロ-ニング〔英文〕

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概要

• 論文の詳細を見る

• It was reported that φ80 lysogens did not adsorb superinfecting phage φ80 and a gene responsible to the phenomenon was named cor (Kozyrev et al., 1982). We found that E. coli containing φ80 genome in lytic cycle also began to show resistance to superinfecting φ80 after 5min of infection. We cloned the cor gene and determined its nucleotide sequence. A putative cor gene product should be 92 amino acids long and have three hydrophobic cores and one hydrophilic region, indicating a possibility of membrane binding protein. The product may interact with φ80 receptor on inner- or outer-membrane of E. coli cells and inhibit the adsorption of superinfecting φ80. The cor gene is supposed to be transcribed from a unique promoter located close to the gene.

• 日本遺伝学会の論文

著者

• MORITA Takashi

  Department of Biochemistry, Meiji Pharmaceutical University

• 松本 緑

  Department of Microbial Genetics, Research Institute for Microbial Dieseases, Osaka University

• ICHIKAWA Norio

  Institute of Biotechnology, Mitsui Toatsu Chemical Co. Ltd.

• TANAKA Shigeo

  Mitsubishi-kasei Institute of Life Sciences

• MATSUSHIRO Aizo

  Department of Microbial Genetics, Research Institute for Microbial Dieseases, Osaka University

• Matsumoto Midori

  Department Of Anesthesia Federation Of National Public Service Personnel Mutual Aid Associations Tac

• Morita Takashi

  Department Of Biochemistry Meiji College Of Pharmacy

• MATSUMOTO Midori

  Department of Microbial Genetics, Research Institute for Microbial Dieseases, Osaka University

• MORITA Takashi

  Department of Microbial Genetics, Research Institute for Microbial Dieseases, Osaka University

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