FINE STRUCTURAL AND BIOCHEMICAL STUDIES ON CELL DEATH OF THE DEVELOPING BAR EYE DISCS IN DROSOPHILA MELANOGASTER
スポンサーリンク
概要
- 論文の詳細を見る
The aspects of degeneration in the Bar eye discs at various developmental stages of Drosophila melanogaster was elucidated microscopically and biochemically. Acid phphosatase was identified histochemically in lysosomes or their derivertives in the degenerating area of the 85-95 hour eye discs. The enzyme reaction appeared to localize selectively in the single membrane-bounded structure or myelin-like figure. The cell debris probably resulting from the resolving process, fail to demonstrate any enzyme activity at the prepupal stage.Biochemical data indicated that the maximum activities of acid phosphatase were shown in eye discs at the 95-hour stage. This is in contrast to the weak acid phosphatase activity detected in eye discs of prepupal stage. However, whole larval homogenates showed maximum value of acid phosphatase activity at the same stage and the post embrionic development. This causal association of increased enzyme activity and histochemical observation in the resolving process of the eye discs suggests that the process of degeneration may be mediated by the lysosome activity, either by the formation of lysosomes or by the synthesis of hydrolytic enzymes. These lysosomes or activities of lysosomal lytic enzyme were reduced by treatment with acetamide. These data suggest that acetamide may act to inhibit the formation of lysosome or the synthesis of hydrolytic enzyme in the Bar eye discs.
- 日本遺伝学会の論文
著者
関連論文
- Cell Affinities of the Bar Eye Disc in Drosophila melanogaster
- Effect of Acetamide on the Bristle Formation in the Brine Shrimp,Artemia salina
- ショウジョウバエBarの眼原基の発生過程における微細構造と細胞化学的研究〔英文〕
- Pleiotropic effects in the four jointed mutant of Drosophila melanogaster.
- EFFECT OF ACETAMIDE ON THE MITOTIC RATE IN EHRLICH ASCITES TUMOR
- FINE STRUCTURAL AND BIOCHEMICAL STUDIES ON CELL DEATH OF THE DEVELOPING BAR EYE DISCS IN DROSOPHILA MELANOGASTER