遺伝的浮動による連鎖不平衡とみかけ上の超優性〔英文〕

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概要

• 論文の詳細を見る

• Random frequency drift causes linkage disequilibrium and associative overdominance, and they have important bearing on the investigation of fitness values of marker alleles. Very often, experimental results merely reflect the effects of genetic background rather than the effect of the markers per se. Approximate magnitude of linkage disequilibrium and associative overdominance were estimated assuming various situations in natural populations. They mainly depend on Nec, the product of the effective population number and the recombination fraction. Also, the magnitude of associative overdominance was estimated assuming two models of experimental populations. In one model, a neutral marker gene is linked with a number of mildly deleterious mutants, and in the other it is linked with overdominant loci. Based on the results, the importance of associative overdominance in both experimental and natural populations was discussed.

• 日本遺伝学会の論文

著者

• Ohta Tomoko

  National Institute Of Genetics

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• 遺伝的浮動による連鎖不平衡とみかけ上の超優性〔英文〕
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