Studies on the host-range mutation in T2 bacteriophage:I. Linkage relationship among markers controlling the host-range and the plaque-type

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The present paper deals with the host-range mutation in T2 bacteriophage and some new linkage relationships among genetic markers controlling the host-specificity and the plaque-types are described.The mutation rate of T2hc (phenotype hc) was about 10-7, and that of T2ht (phenotype ht) was about 10-4-10-5.Crosses between any pairs of independently arising 10 hc-mutants have failed to yield recombinant, indicating that the hc-mutation tend to occur at a single genetic locus.However, recombination experiments between a T2ht-mutant and any one of the T2hc-mutants have shown that these two mutants may occur at least two different loci, respectively.
日本遺伝学会の論文