キイロショウジョウバエにおけるP因子の切り出し頻度と転移頻度の独立性〔英文〕

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概要

• 論文の詳細を見る

• Although a family of transposon, P elements, are used as tools for molecular genetics in Drosophila melanogaster, the molecular details and mechanism of their mobilization process have not been studied extensively. In particular, the relationship between excision and transposition is little understood. We have previously produced a transgenic fly with a P element insertion that is non-autonomous (stable without transposase) and is highly-transposable in the presence of transposase. Using this insertion, we traced its mobilizations following introduction of a stable transposase source. We found a strain that has a 26-bp tandem repeat at the end of the original P element insertion. The 26-bp repeat reduced the frequency of excision although the frequency of transposition was not altered. Our results indicate independence of transposition from excision and importance of terminal repeat in excision.

• 日本遺伝学会の論文

著者

• 吉原 基二郎

  Department of Physics, Faculty of Science, University of Tokyo

• 高須(石川) 悦子

  Department of Physics, Faculty of Science, University of Tokyo

• 堀田 凱樹

  Department of Physics, Faculty of Science, University of Tokyo

• YOSHIHARA Motojiro

  Department of Physics, Faculty of Science, University of Tokyo

• TAKASU-ISHIKAWA Etsuko

  Department of Physics, Faculty of Science, University of Tokyo

• HOTTA Yoshiki

  Department of Physics, Faculty of Science, University of Tokyo

関連論文

• キイロショウジョウバエにおけるP因子の切り出し頻度と転移頻度の独立性〔英文〕
• ショウジョウバエ筋突然変異wings-up Bの電子顕微鏡および電気泳動法による解析〔英文〕
• Isolation of Drosophila genomic clones homologous to the eel sodium channel gene.
• Single P-element insertional mutagenesis in Drosophila melanogaster.

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