Propolis Suppresses Tumor Angiogenesis by Inducing Apoptosis in Tube-Forming Endothelial Cells

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概要

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• We have reported that propolis suppresses tumor-induced angiogenesis in vivo and in vitro, but antiangiogenic mechanism of propolis at cellular level remains unclear. In this study, we observed that propolis not only inhibited tube formation but also induced apoptosis of endothelial cells. These results suggest that propolis exerts its antiangiogenic effects at least in part through induction of apoptosis.

• 社団法人 日本農芸化学会の論文

著者

• Kunimasa Kazuhiro

  Graduate School of Nutritional and Environmental Sciences, University of Shizuoka

• Kobayashi Tomomi

  Graduate School of Nutritional and Environmental Sciences, University of Shizuoka

• KAJI Kazuhiko

  Graduate School of Nutritional and Environmental Sciences, University of Shizuoka

• OHTA Toshiro

  Graduate School of Nutritional and Environmental Sciences, University of Shizuoka

• SAKAMOTO Miwa

  Graduate School of Nutritional and Environmental Sciences, University of Shizuoka

関連論文

• Indole-3-carbinol Suppresses Tumor-Induced Angiogenesis by Inhibiting Tube Formation and Inducing Apoptosis
• Propolis Suppresses Tumor Angiogenesis by Inducing Apoptosis in Tube-Forming Endothelial Cells
• Propolis Suppresses Tumor Angiogenesis by Inducing Apoptosis in Tube-Forming Endothelial Cells
• Nobiletin, a citrus polymethoxyflavonoid, suppresses multiple angiogenesis-related endothelial cell functions and angiogenesis in vivo
• Indole-3-carbinol Suppresses Tumor-Induced Angiogenesis by Inhibiting Tube Formation and Inducing Apoptosis

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