Photochemical stability of lipoic acid and its impact on skin ageing
スポンサーリンク
概要
- 論文の詳細を見る
It is well known that αα-lipoic acid (LA) functions as an essential co-factor of the mitochondrial multi-enzyme complex and thus plays an important role in energy metabolism. Currently, it is attracting attention as a nutritional supplement because of its unique antioxidant properties and broad spectra of cellular functions. Skin protection from photodamage and ageing is one of the functional applications of LA. Medical and cosmetic application has been widely realized in the world. However, LA has a unique structure bearing a distorted five membered 1, 2-dithiolane ring, making it quite vulnerable to UV radiation. The present article briefly reviews skin ageing from the viewpoint of oxidative stress and sun exposure and analyses the photochemical properties of LA. It also discusses the effect of LA to cellular signalling and its adequate applications to treat skin ageing caused by oxidation. Data presented in this review suggest that LA is a powerful anti-ageing agent under the appropriate usage. © 2011 Informa UK, Ltd.
論文 | ランダム
- 043H22 中・長距離選手の血中乳酸4mMトレーニング効果
- Characteristics and Outcomes of Patients With Heart Failure in General Practices and Hospitals : Japanese Cardiac Registry of Heart Failure in General Practice(JCARE-GENERAL)
- 86. 成人男性の体力と安静時血圧 : 末梢循環に関する生理科学的研究, 内分泌に関する生理科学的研究
- 041I23 Onset of blood lactate accumulation (OBLA)に相当する走行スピードと血清脂質,リポ蛋白およびアポ蛋白との関係(4.運動生理,一般研究A)
- 外断熱された建物の室温実測結果について(名寄市E医院入院病棟の場合)